SB 239063
SB 239063 (CAS: 193551-21-2; Formula: C20H21N4O2F) is a bioactive small molecule, identified as a potent inhibitor targeting mitogen-activated protein kinase (MAPK) pathways. This compound, with a molecular weight of 368.40 g/mol, is recognised for its role in cell signalling research and as an approved therapeutic candidate. It is supplied by TSS with an assay of >98% (HPLC) and is typically stored at 2-8°C.
- IUPAC
- trans-1-(4-Hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypyridimidin-4-yl)imidazole

Mitogen-Activated Protein Kinase (MAPK) Inhibitor
SB 239063 acts as an inhibitor of MAPK signalling pathways, which are crucial for various cellular processes including proliferation, differentiation, and survival. Its targeted action makes it a valuable tool for researchers investigating these complex biological cascades.
Cell Signalling Research
This compound is employed in studies focused on understanding cell communication and signal transduction mechanisms. By modulating MAPK activity, researchers can investigate downstream effects and cellular responses in various biological contexts.
Drug Discovery and Development
As an approved therapeutic candidate, SB 239063 is of interest in drug discovery programmes. Its specific inhibitory activity may be explored for potential therapeutic applications in diseases where aberrant MAPK signalling plays a role.
| Molecular weight | 368.40 |
|---|---|
| Empirical formula | C20H21N4O2F |
| Assay | >98% (HPLC) |
| Colour | white |
| Solubility | DMSO: soluble11 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Melting point | 206-207.2 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB 239063 used for?
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SB 239063 is primarily used as a research tool to inhibit mitogen-activated protein kinase (MAPK) pathways and to study cell signalling. It is also recognised as an approved therapeutic candidate.
What is the CAS number and formula for SB 239063?
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The CAS number for SB 239063 is 193551-21-2, and its molecular formula is C20H21N4O2F.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SB 239063 with a purity of >98% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should SB 239063 be handled and stored?
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Handle SB 239063 with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator filter. Store the compound at 2-8°C.
Is SB 239063 a controlled substance?
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The provided data does not indicate that SB 239063 is a controlled substance.
How is SB 239063 shipped?
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SB 239063 is packed and exported according to standard chemical handling and shipping regulations, ensuring product integrity and safety during transit.
How can I request a sample or quote for SB 239063?
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To request a sample or a quote for SB 239063, please contact the Tech Serve Solutions sales team through our official website or designated contact channels.
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