SB 204741
SB 204741 (CAS: 152239-46-8) is a chemical compound with the formula C14H14N4OS and a molecular weight of 286.35 g/mol. This off-white to tan solid is primarily utilised as a research chemical in cell biology and neuroscience. It acts as an antagonist, particularly for GPCR targets. Available from Tech Serve Solutions, it is supplied with a purity of over 98% (HPLC) and is stored at 2-8°C.
- IUPAC
- N-(1-Methyl-1H-5-indolyl)-N′-(3-methyl-5-isothiazolyl)urea

GPCR Modulator Research
SB 204741 functions as an antagonist, making it valuable for studying G protein-coupled receptor (GPCR) pathways. Researchers can use this compound to investigate the roles of specific receptors in cellular signalling and physiological processes.
Neuroscience and Cell Signaling Studies
The compound's activity in neurochemical pathways, indicated by its interaction with receptors like DRD2 and HTR2A, makes it a relevant tool for neuroscience research. It can aid in understanding neurotransmission and cellular communication in the central nervous system.
Drug Discovery and Development
As a compound investigated as a potential therapeutic agent, SB 204741 is useful in early-stage drug discovery. Its antagonist properties can be leveraged to probe biological systems and identify potential lead compounds for further development.
| Molecular weight | 286.35 |
|---|---|
| Empirical formula | C14H14N4OS |
| Assay | >98% (HPLC) |
| Form | solid |
| Colour | off-white to tan |
| Solubility | DMSO: soluble >20 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB 204741 primarily used for?
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SB 204741 is primarily used as a research chemical in cell biology and neuroscience, particularly as an antagonist for GPCRs and in studies related to neurotransmission.
What is the CAS number and chemical formula for SB 204741?
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The CAS number for SB 204741 is 152239-46-8, and its chemical formula is C14H14N4OS.
What grade and purity does Tech Serve Solutions supply for SB 204741?
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Tech Serve Solutions supplies SB 204741 with a purity of >98% (HPLC). This is a research grade chemical and is not represented as USP, BP, or EP.
How should SB 204741 be handled and stored safely?
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SB 204741 is a Warning substance that can cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Store at 2-8°C.
Can I request a sample or quote for SB 204741?
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Yes, to request a sample or a quote for SB 204741, please contact our sales team through the website or by phone.
Is SB 204741 a controlled substance?
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The provided data does not indicate that SB 204741 is a controlled substance.
How is SB 204741 shipped and exported?
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SB 204741 is typically supplied as a solid and is exported according to international shipping regulations for chemical compounds. Please contact us for specific export documentation and details.
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