(S)-(+)-3-Hydroxytetrahydrofuran
(S)-(+)-3-Hydroxytetrahydrofuran (CAS: 86087-23-2, C4H8O2) is a valuable chiral building block. With a molecular weight of 88.11 g/mol, this optically active compound is essential in asymmetric synthesis, particularly for the creation of complex molecules like HIV protease inhibitors. Its utility extends to cell signalling research and as a key intermediate in advanced chemical synthesis, offering researchers and manufacturers a reliable reagent for stereoselective transformations.
- IUPAC
- (S)-(+)-Tetrahydro-3-furanol
- Synonyms
- (S)-(+)-Tetrahydro-3-furanol
Asymmetric Synthesis
This chiral tetrahydrofuran derivative serves as a critical chiral building block in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules.
HIV Protease Inhibitors
It is utilized in the synthesis of building blocks for HIV protease inhibitors, contributing to the development of antiretroviral therapies.
Chemical Synthesis
As a versatile heterocyclic compound, it finds application in various multi-step chemical syntheses where precise stereochemistry is required.
Biochemical Research
The compound can be employed in biochemical research, including studies involving cell signalling enzymes and as a reagent in enzymatic assays.
| Molecular weight | 88.11 |
|---|---|
| Empirical formula | C4H8O2 |
| Assay | 99% |
| Boiling point | 80 °C/15 mmHg(lit.) |
| Density | 1.103 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.45(lit.) |
| Optical activity | [α]20/D +17.5°, c = 2.4 in methanol |
| Optical purity | ee: 99% (GLC) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-3-Hydroxytetrahydrofuran used for?
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It is primarily used as a chiral building block in asymmetric synthesis, particularly for constructing intermediates for HIV protease inhibitors, and in various chemical synthesis and biochemical research applications.
What are the CAS number and formula for (S)-(+)-3-Hydroxytetrahydrofuran?
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(S)-(+)-3-Hydroxytetrahydrofuran has the CAS number 86087-23-2 and the molecular formula C4H8O2.
What grade and purity does Tech Serve Solutions supply for (S)-(+)-3-Hydroxytetrahydrofuran?
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Tech Serve Solutions supplies (S)-(+)-3-Hydroxytetrahydrofuran with an assay of 99% and optical purity of 99% ee (GLC). We do not represent this product as USP, BP, or EP grade.
How should (S)-(+)-3-Hydroxytetrahydrofuran be handled safely?
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Warning: This compound may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields and gloves, and ensure good ventilation. Refer to the safety data sheet for detailed handling instructions.
Is (S)-(+)-3-Hydroxytetrahydrofuran packed and shipped by Tech Serve Solutions?
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Yes, Tech Serve Solutions exports and ships fine chemicals, including (S)-(+)-3-Hydroxytetrahydrofuran, globally. Please contact us for specific shipping details and requirements.
How can I request a quote or sample for (S)-(+)-3-Hydroxytetrahydrofuran?
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To request a quote or sample, please use the 'Request a Quote' or 'Request Sample' buttons on our product page, or contact our sales team directly with your requirements.
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