(S)-(+)-3-Fluoropyrrolidine hydrochloride
(S)-(+)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-53-6) is a chiral building block with the molecular formula C4H8FN · HCl and a molecular weight of 125.57 g/mol. This fluorinated heterocyclic compound is valuable in asymmetric synthesis. It is specifically noted for its role in the development of dipeptidyl peptidase IV inhibitors, making it a key intermediate in pharmaceutical research and development. Supplied by Tech Serve Solutions with an assay of 97%.
Pharmaceutical Intermediates
Serves as a crucial chiral building block in the synthesis of active pharmaceutical ingredients (APIs). Its structure is particularly relevant for developing inhibitors of enzymes like dipeptidyl peptidase IV, contributing to therapeutic advancements.
Asymmetric Synthesis
This optically active fluorinated pyrrolidine derivative is employed in asymmetric synthesis to introduce chirality into target molecules. It enables the stereoselective construction of complex organic compounds.
Medicinal Chemistry Research
Utilised in medicinal chemistry for the design and synthesis of novel drug candidates. The presence of fluorine can modulate pharmacokinetic and pharmacodynamic properties of potential therapeutics.
| Molecular weight | 125.57 |
|---|---|
| Empirical formula | C4H8FN · HCl |
| Assay | 97% |
| Optical activity | [α]20/D +8°, c = 1% in methanol |
| Application | The derived amide acts as an inhibitor of dipeptidyl peptidase IV.1 |
| Melting point | 183-187 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-3-Fluoropyrrolidine hydrochloride used for?
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(S)-(+)-3-Fluoropyrrolidine hydrochloride is used as a chiral building block in asymmetric synthesis, particularly in the development of dipeptidyl peptidase IV inhibitors for pharmaceutical applications.
What is the CAS number and chemical formula?
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The CAS number is 136725-53-6 and the chemical formula is C4H8FN · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-3-Fluoropyrrolidine hydrochloride with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.
How should (S)-(+)-3-Fluoropyrrolidine hydrochloride be handled safely?
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This compound is a Warning substance, harmful if swallowed, and causes skin and eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Ensure adequate ventilation and avoid dust formation.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (S)-(+)-3-Fluoropyrrolidine hydrochloride.
How can I request a sample or quote?
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Please contact our sales team via the website or by phone to request a sample or a quotation for (S)-(+)-3-Fluoropyrrolidine hydrochloride.
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