(S)-(+)-3-Amino-1-Boc-piperidine
(S)-(+)-3-Amino-1-Boc-piperidine (CAS 625471-18-3), a chiral piperidine derivative with the molecular formula C10H20N2O2 and a molecular weight of 200.28 g/mol, serves as a valuable chiral building block. Its protected amine and chiral center make it a key intermediate in asymmetric synthesis and the construction of complex heterocyclic structures for research and development.
- IUPAC
- (S)-1-Boc-3-piperidinamine,tert-Butyl (S)-3-amino-1-piperidinecarboxylate
- Synonyms
- tert-Butyl (S)-3-amino-1-piperidinecarboxylate
Chiral Building Block in Organic Synthesis
Utilised as a stereodefined intermediate for the synthesis of complex chiral molecules. The Boc-protected amine allows for selective functionalization and manipulation in multi-step synthetic pathways.
Pharmaceutical Intermediate
Serves as a crucial scaffold component in the development of novel pharmaceutical agents. Its piperidine ring structure is found in many biologically active compounds, making it relevant for drug discovery programmes.
Asymmetric Synthesis
Enables the stereocontrolled introduction of a chiral piperidine moiety into target molecules. Essential for constructing enantiomerically pure compounds where specific stereochemistry is critical for activity.
Heterocyclic Chemistry
A versatile precursor for synthesizing various substituted piperidine derivatives and other nitrogen-containing heterocycles. Facilitates the exploration of new chemical space in medicinal chemistry and materials science.
| Molecular weight | 200.28 |
|---|---|
| Empirical formula | C10H20N2O2 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]/D +29.5±3°, c = 1 in DMF |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-3-Amino-1-Boc-piperidine used for?
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(S)-(+)-3-Amino-1-Boc-piperidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceutical agents and other complex heterocyclic compounds.
What are the CAS number and formula for (S)-(+)-3-Amino-1-Boc-piperidine?
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The CAS number for (S)-(+)-3-Amino-1-Boc-piperidine is 625471-18-3, and its empirical formula is C10H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-3-Amino-1-Boc-piperidine with a purity of ≥98.0% (TLC). TSS does not represent this product as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling considerations for (S)-(+)-3-Amino-1-Boc-piperidine?
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This compound is classified as a Warning (GHS07) and may cause harm if swallowed (H302), skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Handle in a well-ventilated area.
How is (S)-(+)-3-Amino-1-Boc-piperidine supplied and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (S)-(+)-3-Amino-1-Boc-piperidine, adhering to international shipping regulations.
How can I request a sample or quote for (S)-(+)-3-Amino-1-Boc-piperidine?
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To request a sample or a quote for (S)-(+)-3-Amino-1-Boc-piperidine, please contact our sales team through the TSS website or by phone.
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