(S)-(+)-3-Chloro-1,2-propanediol
(S)-(+)-3-Chloro-1,2-propanediol (CAS 60827-45-4) is a chiral building block with the linear formula ClCH2CH(OH)CH2OH and a molecular weight of 110.54 g/mol. This optically active polyol is valuable in asymmetric synthesis and organic chemical synthesis. Its defined stereochemistry makes it a key intermediate for constructing complex chiral molecules, finding utility in various research and development applications within the chemical and pharmaceutical industries.
- IUPAC
- (S)-α-Glycerol chlorohydrin
- Synonyms
- ClCH2CH(OH)CH2OH(S)-α-Glycerol chlorohydrin
Chiral Synthesis Intermediate
Serves as a crucial chiral building block in the synthesis of enantiomerically pure compounds. Its structure allows for stereoselective transformations, enabling the creation of complex molecules with defined chirality.
Organic Synthesis Reagent
Utilised in organic chemistry for the introduction of functionalised chiral fragments. The presence of both hydroxyl groups and a chlorine atom offers versatile reactivity for further chemical modifications.
Pharmaceutical Research
Employed in the development of novel pharmaceutical agents where specific stereochemistry is essential for biological activity. It acts as a precursor to various active pharmaceutical ingredients.
| Molecular weight | 110.54 |
|---|---|
| Linear formula | ClCH2CH(OH)CH2OH |
| Assay | 97% |
| Boiling point | 213 °C(lit.) |
| Density | 1.322 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.480(lit.) |
| Optical purity | ee: 97% (GLC) |
Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2689 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 21-25-41 |
| Safety statements (S) | 26-28-39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-3-Chloro-1,2-propanediol used for?
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(S)-(+)-3-Chloro-1,2-propanediol is primarily used as a chiral building block in asymmetric synthesis and general organic chemical synthesis, particularly in pharmaceutical research for creating enantiomerically pure compounds.
What are the CAS number and chemical formula for (S)-(+)-3-Chloro-1,2-propanediol?
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The CAS number is 60827-45-4, and the linear formula is ClCH2CH(OH)CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-3-Chloro-1,2-propanediol with an assay of 97% and an optical purity of ee: 97% (GLC). We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with (S)-(+)-3-Chloro-1,2-propanediol?
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(S)-(+)-3-Chloro-1,2-propanediol is classified with GHS symbols GHS05 and GHS06, carrying the signal word 'Danger'. It has hazard statements H301 (Toxic if swallowed), H312 (Toxic in contact with skin), and H318 (Causes serious eye damage). Appropriate personal protective equipment, including eye protection, gloves, and respiratory protection, is essential during handling.
How is (S)-(+)-3-Chloro-1,2-propanediol packed, shipped, and exported?
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We ensure secure and compliant packaging suitable for its hazard classification. Shipping and export adhere to all relevant international regulations for hazardous materials, including UN 2689 classification.
How can I request a sample or a quote for (S)-(+)-3-Chloro-1,2-propanediol?
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You can request a sample or a quote by contacting our sales department via phone or email through the details provided on our website. Please reference the product name and CAS number.
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