(S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]methoxy-methyl}pyrrolidine hydrochloride
(S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]methoxy-methyl}pyrrolidine hydrochloride (CAS 1217463-07-4) is a chiral organocatalyst with a molecular weight of 575.82 g/mol. This compound, featuring a pyrrolidine core and multiple trifluoromethylphenyl groups, is primarily utilised in asymmetric synthesis. It serves as a valuable reagent in chemical synthesis and is particularly employed in the development of chiral catalysts and ligands.
- Synonyms
- C22H17F12NO· HCl
![(S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]methoxy-methyl}pyrrolidine hydrochloride (C22H17F12NO· HCl) — chemical structure, CAS 1217463-07-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1217463-07-4.png&w=3840&q=75)
Asymmetric Synthesis
This compound is a key organocatalyst used to promote enantioselective transformations. Its chiral structure enables the stereoselective formation of new chiral centres in organic molecules.
Chiral Catalysis
It functions as a chiral ligand or catalyst in various metal-catalyzed and organocatalytic reactions. This facilitates the synthesis of enantiomerically enriched products, crucial in pharmaceutical development.
Chemical Synthesis
As a specialized reagent, it contributes to complex organic synthesis pathways. Its unique structural features are leveraged for specific synthetic challenges requiring chiral induction.
Proline-Based Organocatalysis
Derived from proline, this catalyst belongs to a class of highly effective organocatalysts. It is employed in reactions where proline derivatives are known to provide excellent stereocontrol.
| Molecular weight | 575.82 |
|---|---|
| Empirical formula | C22H17F12NO· HCl |
| Assay | ≥98.5% (HPLC)99% |
| Optical purity | enantiomeric excess: ≥97.5% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]methoxy-methyl}pyrrolidine hydrochloride used for?
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(S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]methoxy-methyl}pyrrolidine hydrochloride is primarily used as a chiral catalyst and reagent in asymmetric synthesis and chemical synthesis, particularly within proline-based organocatalysis and chiral catalysis.
What is the CAS number and formula for this chemical?
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The CAS number is 1217463-07-4 and the empirical formula is C22H17F12NO· HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥98.5% (HPLC) and 99% purity, and an enantiomeric excess of ≥97.5% (HPLC). We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should (S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]methoxy-methyl}pyrrolidine hydrochloride be handled safely?
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Handle this compound with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3.
Is this product suitable for storage at refrigerated temperatures?
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Yes, the recommended storage temperature for this product is between 2-8°C to maintain its integrity and efficacy.
How is this product packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are carefully packed according to international shipping regulations to ensure safe transit. Specific packaging details can be provided upon request.
How can I request a sample or quote for this chemical?
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Please contact our sales team directly through our website or by phone to request a sample or a formal quotation for (S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]methoxy-methyl}pyrrolidine hydrochloride.
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