(S)-2-[[(1R,2R)-2-[[[3,5-Bis(tert-butyl)-2-hydroxyphenyl]methylene]amino]cyclohexyl]thioureido]-N-benzyl-N,3,3-trimethylbutanamide
(S)-2-[[(1R,2R)-2-[[[3,5-Bis(tert-butyl)-2-hydroxyphenyl]methylene]amino]cyclohexyl]thioureido]-N-benzyl-N,3,3-trimethylbutanamide (CAS 479423-24-0) is a chiral thiourea ligand with a molecular weight of 606.90 g/mol. This compound is primarily employed as a catalyst in asymmetric synthesis, specifically noted for its application in the Mannich reaction. Its defined stereochemistry and functional groups make it a valuable tool for stereoselective transformations in chemical synthesis. Tech Serve Solutions supplies this reagent for research and development purposes.
- IUPAC
- (2S)-2-[[[[(1R,2R)-2-[[[3,5-Bis(tert-butyl)-2-hydroxyphenyl]methylene]amino]cyclohexyl]amino]thioxomethyl]amino]-N-benzyl-N,3,3-trimethylbutanamide,(2S)-2-[[[[(1R,2R)-2-[[[3,5-Bis(1,1-dimethylethyl)-2-hydroxyphenyl]methylene]amino]cyclohexyl]amino]thioxomethyl]amino]-N,3,3-trimethyl-N-(phenylmethyl)butanamide
- Synonyms
- 3,3-trimethylbutanamide,479423-24-0, C36H54N4O2S
![(S)-2-[[(1R,2R)-2-[[[3,5-Bis(tert-butyl)-2-hydroxyphenyl]methylene]amino]cyclohexyl]thioureido]-N-benzyl-N,3,3-trimethylbutanamide (C36H54N4O2S) — chemical structure, CAS 479423-24-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F479423-24-0.png&w=3840&q=75)
Catalyst for Asymmetric Mannich Reactions
This chiral thiourea serves as an effective catalyst for asymmetric Mannich reactions, facilitating the stereoselective formation of carbon-carbon bonds. Its specific structure enables high enantioselectivity in the synthesis of valuable chiral products.
Ligand in Chiral Catalysis
As a sophisticated chiral ligand, it can be employed in various metal-catalyzed asymmetric transformations. Its unique architecture provides a chiral environment that influences the stereochemical outcome of catalytic processes.
Reagent in Organic Synthesis
Beyond its catalytic roles, this compound is a useful reagent in complex organic synthesis, particularly where precise stereochemical control is required. It can be incorporated into synthetic routes for pharmaceuticals and fine chemicals.
| Molecular weight | 606.90 |
|---|---|
| Empirical formula | C36H54N4O2S |
| Grade | technical grade |
| Optical activity | [α]22/D -99°, c = 1 in chloroform |
| Application | Catalyst for the Mannich reaction5 |
| Melting point | 153-163 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-2-[[(1R,2R)-2-[[[3,5-Bis(tert-butyl)-2-hydroxyphenyl]methylene]amino]cyclohexyl]thioureido]-N-benzyl-N,3,3-trimethylbutanamide used for?
+
This compound is primarily used as a catalyst for the asymmetric Mannich reaction and as a chiral ligand in various asymmetric synthesis applications.
What are the CAS number and molecular formula for this chemical?
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The CAS number is 479423-24-0 and the empirical formula is C36H54N4O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as technical grade. We do not represent it as USP, BP, or EP grade.
How should this chemical be handled safely?
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This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves should be used. Avoid breathing dust and ensure adequate ventilation.
Is this chemical a controlled substance?
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The provided data does not indicate that this chemical is a controlled substance.
How is this product packed and shipped?
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This product is packed according to standard chemical handling procedures. Tech Serve Solutions exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally.
How can I request a sample or quote for this product?
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To request a sample or a quote, please contact our sales department through the TSS website or by calling our customer service line.
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