(S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol
(S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol (CAS 908338-44-3), a chiral BINOL derivative with the empirical formula C50H58O2 and a molecular weight of 690.99 g/mol, is a highly effective ligand and catalyst in asymmetric synthesis. Its sterically hindered biaryl structure facilitates enantioselective transformations, making it valuable in the production of complex chiral molecules.
- IUPAC
- (1S)-3,3′-Bis[2,4,6-tris(1-methylethyl)phenyl]-1,1′-binaphthalene-2,2′-diol
- Synonyms
- (1S)-3,3′-Bis[2,4,6-tris(1-methylethyl)phenyl]-1,1′-binaphthalene-2,2′-diol6-triisopropylphenyl)-1,1′-bi-2-naphthol908338-44-3C50H58O2

Chiral Ligand in Asymmetric Catalysis
This compound serves as a crucial chiral ligand in various metal-catalyzed asymmetric reactions. It enables high enantioselectivity in transformations such as additions, reductions, and cycloadditions, leading to the synthesis of optically pure compounds.
Asymmetric Synthesis
Utilised extensively in asymmetric synthesis, it promotes the formation of specific enantiomers in organic molecules. Its structure is particularly suited for reactions requiring bulky chiral environments, enhancing stereochemical control.
Privileged Ligand
As a privileged ligand, it exhibits broad applicability across different catalytic systems and substrate classes. Its robust framework allows for predictable performance in complex synthetic challenges.
| Molecular weight | 690.99 |
|---|---|
| Empirical formula | C50H58O2 |
| Assay | ≥95.5% (HPLC)96% |
| Optical purity | ee: ≥99.0 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, facilitating the enantioselective production of chiral molecules.
What is the CAS number and formula for this chemical?
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The CAS number is 908338-44-3, and the empirical formula is C50H58O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥95.5% (HPLC) and an optical purity (ee) of ≥99.0%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should (S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It carries a WGK Germany classification of 3, indicating significant hazard.
How is this chemical packed and shipped?
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Tech Serve Solutions reliably packs and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary safety and shipping regulations.
How can I request a sample or quote for this chemical?
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Please contact our sales team directly to request a sample or a quotation for (S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol.
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