(S)-2-[[(1R,2R)-2-Aminocyclohexyl]thioureido]-N-benzyl-N,3,3-trimethylbutanamide
(S)-2-[[(1R,2R)-2-Aminocyclohexyl]thioureido]-N-benzyl-N,3,3-trimethylbutanamide (CAS 479423-21-7), with the molecular formula C21H34N4OS and a molecular weight of 390.59, is a chiral thiourea derivative. It is primarily utilised as a catalyst or reagent in asymmetric synthesis, facilitating the stereoselective formation of chiral molecules. This compound plays a key role in advanced chemical synthesis and the development of stereochemically pure substances.
- IUPAC
- (2S)-2-[[[[(1R,2R)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N-3,3-trimethyl-N-(phenylmethyl)butanamide,(S)-2-[[[[(1R,2R)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N-benzyl-N-3,3-trimethylbutanamide
- Synonyms
- (2S)-2-[[[[(1R,2R)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N-3,3-trimethyl-N-(phenylmethyl)butanamide(S)-2-[[[[(1R,2R)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N-benzyl-N-3,3-trimethylbutanamide
![(S)-2-[[(1R,2R)-2-Aminocyclohexyl]thioureido]-N-benzyl-N,3,3-trimethylbutanamide (C21H34N4OS) — chemical structure, CAS 479423-21-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F479423-21-7.png&w=3840&q=75)
Chiral Catalyst in Asymmetric Synthesis
This thiourea derivative serves as an effective organocatalyst for various asymmetric transformations. It is particularly valuable in promoting enantioselective reactions, enabling the synthesis of optically pure compounds crucial for pharmaceuticals and fine chemicals.
Reagent for Stereoselective Reactions
In chemical synthesis, (S)-2-[[(1R,2R)-2-Aminocyclohexyl]thioureido]-N-benzyl-N,3,3-trimethylbutanamide acts as a key reagent. Its chiral structure allows for precise control over stereochemistry, leading to highly enantiomerically enriched products.
Ligand Development
The compound's structure lends itself to applications in the development of novel chiral ligands. These ligands are essential for metal-catalyzed asymmetric reactions, expanding the scope of stereoselective synthesis.
| Molecular weight | 390.59 |
|---|---|
| Empirical formula | C21H34N4OS |
| Assay | 95% |
| Optical activity | [α]20/D +19.0°, c = 1 in chloroform |
| Melting point | 71-85 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-2-[[(1R,2R)-2-Aminocyclohexyl]thioureido]-N-benzyl-N,3,3-trimethylbutanamide used for?
+
This compound is primarily used as a chiral catalyst or reagent in asymmetric synthesis for the stereoselective formation of chiral molecules.
What are the CAS number and molecular formula?
+
The CAS number is 479423-21-7, and the empirical formula (Hill notation) is C21H34N4OS.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound with an assay of 95%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should this chemical be handled?
+
Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation; avoid breathing dust. Refer to the safety data sheet for comprehensive handling information. It is classified as causing skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).
How is this product packed and shipped?
+
This chemical is available from Tech Serve Solutions, a global supplier and exporter. Packaging details are confirmed upon order.
How can I request a sample or quote?
+
Please contact Tech Serve Solutions directly to request a sample or a quotation for (S)-2-[[(1R,2R)-2-Aminocyclohexyl]thioureido]-N-benzyl-N,3,3-trimethylbutanamide.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis