Renin Substrate Tetradecapeptide porcine
Renin Substrate Tetradecapeptide porcine (CAS: 20845-02-7), with the empirical formula C85H123N21O20 and a molecular weight of 1759.01 g/mol, is a synthetic peptide analogue of the N-terminal portion of angiotensinogen. This tetradecapeptide serves as a crucial substrate in biochemical research, particularly for studying the renin-angiotensin-aldosterone system (RAAS) and its role in blood pressure regulation. It is primarily used in cell biology and neuroscience research.
- IUPAC
- Angiotensinogen 1-14,Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-leu-Val-Tyr-Ser
Renin-Angiotensin System (RAAS) Research
Used as a substrate to investigate the enzymatic activity of renin, a key enzyme in the RAAS pathway responsible for converting angiotensinogen to angiotensin I. This facilitates studies on blood pressure regulation and related physiological processes.
Peptide Synthesis and Analysis
Serves as a reference standard or building block in the synthesis and characterisation of peptide analogues and related compounds. Its defined sequence and purity are valuable for analytical method development.
Cellular Signaling Studies
Applied in cell-based assays to understand signalling cascades involving angiotensin peptides and their receptors. This aids in elucidating mechanisms of cellular responses to hormonal stimuli.
Neuroscience Research
Investigates the role of the RAAS components in the central nervous system, including their influence on neuronal activity, behaviour, and neuroprotection.
| Molecular weight | 1759.01 |
|---|---|
| Empirical formula | C85H123N21O20 |
| Assay | ≥97% (HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Renin Substrate Tetradecapeptide porcine used for?
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Renin Substrate Tetradecapeptide porcine is primarily used in biochemical research, particularly for studying the renin-angiotensin-aldosterone system (RAAS), blood pressure regulation, cellular signalling, and in neuroscience research.
What is the CAS number and formula for Renin Substrate Tetradecapeptide porcine?
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The CAS number is 20845-02-7 and the empirical formula is C85H123N21O20.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Renin Substrate Tetradecapeptide porcine be handled and stored?
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Handle with appropriate personal protective equipment including eyeshields and gloves. A type N95 respirator filter is recommended. Store at −20°C. The product has a WGK (Germany) rating of 3, indicating a high hazard to water.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packing, shipping, and export details are available upon request, adhering to all relevant regulations.
How can I request a sample or quote for Renin Substrate Tetradecapeptide porcine?
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Please contact our sales team directly via the website or by phone to request a sample or obtain a quotation for Renin Substrate Tetradecapeptide porcine (CAS: 20845-02-7).
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