RepSox

CAS 446859-33-2C17H13N5Cell Biology

RepSox (CAS: 446859-33-2), with the molecular formula C17H13N5 and a molecular weight of 287.32, is a bioactive small molecule. This compound is recognised for its role in cell signalling pathways, particularly as an inhibitor of Transforming Growth Factor-beta (TGF-β). Its applications are primarily within research settings focused on cell biology, neuroscience, and the study of cytokines and growth factors.

IUPAC: E-616452; 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine
Synonyms: 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine

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RepSox (C17H13N5) — chemical structure, CAS 446859-33-2; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyCytokines and Growth FactorsCytokinesGrowth Factors and HormonesTGF-β Inhibitors

01 /Applications

TGF-β Signalling Inhibition

RepSox functions as a potent inhibitor of the TGF-β signalling pathway. This makes it a valuable tool for researchers investigating cellular processes regulated by TGF-β, including cell growth, differentiation, and apoptosis.

Cell Biology Research

As a key modulator of cell signalling, RepSox is utilised in various cell biology studies. It aids in understanding complex cellular responses and the mechanisms underlying development and disease.

Neuroscience Applications

The compound's involvement in cell signalling pathways extends to neuroscience research. It can be employed to study neuronal development, function, and the impact of TGF-β signalling in the nervous system.

Cytokine and Growth Factor Studies

RepSox serves as a critical reagent for investigating the roles of cytokines and growth factors. Its inhibitory action on TGF-β allows for detailed examination of these crucial biological molecules.

02 /Properties

Molecular weight	287.32
Empirical formula	C17H13N5
Assay	≥98% (HPLC)
Form	solid
Solubility	DMSO: >20 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Transport (UN / ADR)	UN 2811 6.1 / PGIII
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

446859-33-2

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is RepSox used for?

RepSox is primarily used in research as an inhibitor of the Transforming Growth Factor-beta (TGF-β) signalling pathway, impacting cell biology, neuroscience, and studies involving cytokines and growth factors.

What are the CAS number and formula for RepSox?

The CAS number for RepSox is 446859-33-2, and its molecular formula is C17H13N5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies RepSox with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should RepSox be handled and stored?

RepSox is classified as acutely toxic if swallowed (H301) and requires careful handling. It should be stored at 2-8°C. Always consult the Safety Data Sheet (SDS) and use appropriate personal protective equipment (PPE) when handling.

Is RepSox a controlled substance?

The provided data indicates RepSox is classified under UN 2811 6.1 / PGIII, suggesting it is transported as a toxic solid, but it is not listed as a controlled substance in this context.

How can I request a quote or sample for RepSox?

To request a quote or sample of RepSox, please contact our sales team through the TSS website or via the provided contact details, specifying the product CAS number 446859-33-2.

How is RepSox typically packed and exported?

RepSox is typically supplied as a solid and is packed according to international shipping regulations for hazardous materials, including UN 2811 classification. We export globally.