Resiniferatoxin
Resiniferatoxin (CAS 57444-62-9), with the molecular formula C37H40O9 and a molecular weight of 628.71 g/mol, is a potent natural compound isolated from Euphorbia poisonii. It is a significant research chemical belonging to the vanilloid class, primarily recognised for its powerful biological activity and use in neurobiology and cell signaling studies. Its extreme potency requires careful handling and precise application in research settings.
Neuroscience Research
Resiniferatoxin is widely utilized in neuroscience research to study the function and activation of transient receptor potential vanilloid 1 (TRPV1) channels. Its agonistic activity on TRPV1 makes it a valuable tool for investigating pain pathways and sensory neurobiology.
Cell Signaling Studies
This compound serves as a critical reagent in cell signaling research, enabling scientists to explore downstream effects of TRPV1 activation. It helps in understanding cellular responses to stimuli, particularly in excitable cells like neurons.
Pharmacological Investigations
Resiniferatoxin is employed in pharmacological studies to investigate potential therapeutic applications related to pain management and other conditions modulated by TRPV1. Its potent effects provide insights into receptor-ligand interactions.
Bioactive Compound Analysis
As a well-characterised phytochemical, Resiniferatoxin is used in the analysis of bioactive small molecules derived from natural sources. Its isolation and study contribute to understanding plant-derived medicinal compounds.
| Molecular weight | 628.71 |
|---|---|
| Empirical formula | C37H40O9 |
| Assay | ~95% |
| Storage temperature | −20°C |
| Biological source | from Euphorbia poisonii |
Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-35 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Trpv1(83810) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Resiniferatoxin primarily used for?
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Resiniferatoxin is primarily used in neuroscience research for studying TRPV1 channels, pain pathways, and cell signaling. It is a potent biological probe requiring careful handling.
What are the CAS number and formula for Resiniferatoxin?
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The CAS number for Resiniferatoxin is 57444-62-9, and its empirical formula (Hill Notation) is C37H40O9.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Resiniferatoxin with an assay of approximately 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade; it is intended for research purposes.
What are the primary safety hazards associated with Resiniferatoxin?
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Resiniferatoxin is classified under GHS05 and GHS06, with the signal word 'Danger'. It carries hazard statements H301 (Toxic if swallowed) and H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, is essential. It is classified as T (Toxic) with risk statements R25 (Toxic if swallowed) and R35 (Causes severe burns) in Europe.
How is Resiniferatoxin typically shipped and exported?
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Resiniferatoxin is classified under UN 2811, hazard class 6.1 (Toxic substances), Packing Group III. Tech Serve Solutions ensures proper packaging and adherence to international shipping regulations for hazardous materials.
How can I request a sample or quote for Resiniferatoxin?
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To request a sample or a quotation for Resiniferatoxin, please contact our sales team through the website or by phone. We will be happy to assist you with your research needs.
Is Resiniferatoxin a controlled substance?
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The provided data does not indicate that Resiniferatoxin is a controlled substance. However, users should always comply with local regulations regarding its possession and use.
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