D-Serine methyl ester hydrochloride
D-Serine methyl ester hydrochloride (CAS: 5874-57-7) is a derivative of the amino acid serine, with the molecular formula HOCH2CH(NH2)CO2CH3·HCl and a molecular weight of 155.58 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its specific stereochemistry makes it useful in the creation of complex molecules and for studying biological processes.

Peptide Synthesis
D-Serine methyl ester hydrochloride is employed as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis, facilitating the incorporation of D-serine residues into peptide chains.
Chemical Biology Research
It acts as a tool compound for researchers investigating the roles of non-canonical amino acids in biological systems, protein structure, and enzyme mechanisms.
Organic Synthesis Intermediate
The compound serves as a versatile intermediate in the synthesis of various organic molecules, including pharmaceuticals and complex chiral compounds.
| Molecular weight | 155.58 |
|---|---|
| Linear formula | HOCH2CH(NH2)CO2CH3·HCl |
| Assay | 98% |
| Optical activity | [α]20/D −4°, c = 4 in ethanol |
| Melting point | 163-166 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Serine methyl ester hydrochloride used for?
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D-Serine methyl ester hydrochloride is primarily used as a building block in peptide synthesis, in chemical biology research, and as an intermediate in organic synthesis.
What is the CAS number and formula for D-Serine methyl ester hydrochloride?
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The CAS number is 5874-57-7 and the linear formula is HOCH2CH(NH2)CO2CH3·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Serine methyl ester hydrochloride with an assay of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should D-Serine methyl ester hydrochloride be handled?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a P1 (EN143) or N95 respirator filter, in a well-ventilated area. Avoid contact with skin and eyes.
Is D-Serine methyl ester hydrochloride a controlled substance?
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Based on the provided data, there is no indication that D-Serine methyl ester hydrochloride is a controlled substance.
How is D-Serine methyl ester hydrochloride shipped?
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D-Serine methyl ester hydrochloride is carefully packed and exported by Tech Serve Solutions, adhering to all relevant shipping regulations for fine chemicals.
How can I request a quote or sample?
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To request a quote or sample of D-Serine methyl ester hydrochloride, please contact our sales department through the website or by phone.
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