(R,R)-(−)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II)
(R,R)-(−)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II), CAS 176763-62-5, with the formula [[[(CH3)3C]2C6H2-2-(O-)CH=N]2C6H10]Co and a molecular weight of 603.74, is a chiral cobalt complex. It serves as a highly effective catalyst in asymmetric synthesis. Its primary applications involve the hydrolytic kinetic resolution of terminal epoxides and the enantioselective ring opening of meso epoxides, facilitating the synthesis of valuable chiral intermediates.
- Synonyms
- N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II),176763-62-5, [[[(CH3)3C]2C6H2-2-(O-)CH=N]2C6H10]Co

Catalyst for Hydrolytic Kinetic Resolution
This cobalt complex is an established catalyst for the hydrolytic kinetic resolution of terminal epoxides. It enables the selective reaction of one enantiomer, allowing for the separation and isolation of chiral diols or unreacted epoxides.
Enantioselective Epoxide Ring Opening
The compound efficiently catalyses the enantioselective ring opening of meso epoxides. This application is crucial for the synthesis of chiral building blocks with high stereochemical purity, essential in pharmaceutical and fine chemical production.
Asymmetric Synthesis
As a chiral catalyst, it plays a significant role in asymmetric synthesis, promoting the formation of specific enantiomers in chemical reactions. This is vital for producing enantiomerically pure compounds.
| Molecular weight | 603.74 |
|---|---|
| Linear formula | [[[(CH3)3C]2C6H2-2-(O-)CH=N]2C6H10]Co |
| Application | Catalyst for the hydrolytic kinetic resolution of terminal epoxides1 and the enantioselective ring opening of meso epoxides.2 |
| Melting point | >350 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R,R)-(−)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) used for?
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(R,R)-(−)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) is used as a catalyst for the hydrolytic kinetic resolution of terminal epoxides and for the enantioselective ring opening of meso epoxides, facilitating asymmetric synthesis.
What are the CAS number and formula for this cobalt complex?
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The CAS number is 176763-62-5, and the formula is [[[(CH3)3C]2C6H2-2-(O-)CH=N]2C6H10]Co.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and chemical synthesis purposes. The specific grade and purity are available upon request. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling this chemical?
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This compound is classified as harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). When handling, it is essential to wear a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals. We can arrange for the export of this compound, adhering to all relevant international shipping regulations.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team through the website or by phone. Provide the product name and CAS number (176763-62-5) for prompt service.
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