(R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine
(R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine (CAS: 68737-65-5), with a molecular weight of 142.24 g/mol, is a chiral diamine. It is valuable in asymmetric synthesis due to its specific stereochemistry. This compound serves as a crucial building block and ligand in various organic syntheses, facilitating the creation of complex molecules with high enantiomeric purity. Its applications span research and development within the pharmaceutical and fine chemical industries.
- IUPAC
- (R,R)-(−)-N,N′-Dimethyl-1,2-diaminocyclohexane,trans-1,2-Bis(methylamino)cyclohexane
- Synonyms
- (R,R)-(−)-N,N′-Dimethyl-1,2-diaminocyclohexanetrans-1,2-Bis(methylamino)cyclohexane
Asymmetric Synthesis
This chiral diamine is widely employed as a ligand or auxiliary in asymmetric catalysis, enabling the stereoselective synthesis of enantiomerically enriched compounds crucial for pharmaceuticals and agrochemicals.
Chiral Building Block
It acts as a fundamental chiral building block in organic synthesis, allowing for the introduction of stereochemical complexity into target molecules.
Ligand for Metal Catalysis
The compound's structure makes it an effective ligand for various transition metal catalysts, promoting stereochemical control in reactions such as hydrogenations and C-C bond formations.
| Molecular weight | 142.24 |
|---|---|
| Empirical formula | C8H18N2 |
| Assay | ≥97.0% (GC) |
| Optical activity | [α]/D -145±5°, c = 4.47 in chloroform |
| Storage temperature | 2-8°C |
| Melting point | 39-44 °C |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 74 °C / 165.2 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine used for?
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This compound is primarily used in asymmetric synthesis as a chiral building block and as a ligand in metal-catalyzed reactions to achieve stereoselective outcomes.
What is the CAS number and formula for (R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine?
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The CAS number is 68737-65-5 and the empirical formula is C8H18N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine with a purity of ≥97.0% (GC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should (R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine be handled safely?
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This compound is classified as corrosive and harmful if swallowed (H314, H302). Handle with appropriate personal protective equipment, including gloves, eye protection (goggles and face shield), and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.
Is (R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine, adhering to all necessary regulations.
How can I request a sample or quote for (R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine?
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Please contact our sales team via the website or direct inquiry to request a sample or a competitive quote for (R,R)-(−)-N,N′-Dimethyl-1,2-cyclohexanediamine.
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