2-Amino-3-(trifluoromethyl)benzoic acid
2-Amino-3-(trifluoromethyl)benzoic acid (CAS: 313-12-2), with the molecular formula CF3C6H3-2-(NH2)CO2H and a molecular weight of 205.13 g/mol, is a valuable aromatic amino acid derivative. It serves as a key building block in chemical synthesis, particularly in the development of novel compounds within chemical biology and peptide chemistry. Its trifluoromethyl substituent imparts unique electronic properties, making it useful for creating advanced materials and pharmaceutical intermediates.
- IUPAC
- 3-(Trifluoromethyl)anthranilic acid
Chemical Synthesis Intermediate
This compound is extensively used as an intermediate in organic synthesis for the construction of complex molecules. Its reactive amino and carboxylic acid groups allow for diverse derivatisation.
Peptide and Unnatural Amino Acid Chemistry
Incorporation into peptides allows for the creation of unnatural amino acid derivatives, which can modulate peptide structure, stability, and biological activity. This is vital in drug discovery and biochemical research.
Pharmaceutical Research and Development
It acts as a precursor or building block in the synthesis of active pharmaceutical ingredients (APIs). The trifluoromethyl group can enhance lipophilicity and metabolic stability of drug candidates.
Chemical Biology Probes
Used in the design and synthesis of specialised molecules for investigating biological pathways and targets. Its unique structure can aid in developing novel diagnostic or therapeutic agents.
| Molecular weight | 205.13 |
|---|---|
| Linear formula | CF3C6H3-2-(NH2)CO2H |
| Assay | 98% dry basis |
| Impurities tested | ≤4.0% Water (Karl Fischer) |
| Melting point | 157-160 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-3-(trifluoromethyl)benzoic acid used for?
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2-Amino-3-(trifluoromethyl)benzoic acid is used as an intermediate in chemical synthesis, particularly in peptide chemistry, chemical biology, and the development of pharmaceutical intermediates and unnatural amino acid derivatives.
What are the CAS number and molecular formula for this compound?
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The CAS number is 313-12-2, and the molecular formula is CF3C6H3-2-(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-3-(trifluoromethyl)benzoic acid with an assay of 98% on a dry basis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety hazards associated with this chemical?
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This compound carries a Warning signal word and is classified with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn when handling.
How is 2-Amino-3-(trifluoromethyl)benzoic acid packed and shipped?
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We pack and ship chemicals according to international regulations for hazardous materials, ensuring safe transit for domestic and export orders. Please contact us for specific shipping details.
How can I request a sample or quote for this product?
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To request a sample or obtain a quotation, please use the contact form on our website or email our sales department directly, referencing the product name and CAS number.
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