2-Amino-3-(trifluoromethyl)pyridine
2-Amino-3-(trifluoromethyl)pyridine (CAS: 183610-70-0; Formula: C6H5F3N2; Molar Mass: 162.11 g/mol) is a fluorinated pyridine derivative. This heterocyclic building block is recognised for its utility in organic synthesis, particularly in the development of novel chemical entities. Its structure, featuring both an amine and a trifluoromethyl group on a pyridine ring, makes it a valuable intermediate for creating complex molecules, especially within pharmaceutical and agrochemical research sectors.
- IUPAC
- 3-(Trifluoromethyl)-2-pyridinamine
- Synonyms
- 3-(Trifluoromethyl)-2-pyridinamine

Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) where the trifluoromethylpyridine scaffold is a key structural motif. This compound can be elaborated into various drug candidates.
Agrochemical Synthesis
Serves as a building block for creating new agrochemical compounds, such as herbicides, insecticides, or fungicides. The trifluoromethyl group often imparts desirable properties to these agents.
Organic Synthesis Reagent
A versatile reagent in general organic synthesis for introducing the 3-(trifluoromethyl)pyridin-2-yl moiety into target molecules. It is suitable for various coupling and derivatisation reactions.
Material Science Research
Can be employed in the development of specialised materials, where its unique electronic and structural properties contribute to material performance.
| Molecular weight | 162.11 |
|---|---|
| Empirical formula | C6H5F3N2 |
| Assay | 97% |
| Melting point | 66-71 °C |

Hazard statements
- H301Toxic if swallowed
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36-43 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-3-(trifluoromethyl)pyridine used for?
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2-Amino-3-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, finding applications in the development of pharmaceuticals, agrochemicals, and specialised materials. It is an intermediate for creating complex molecules.
What are the CAS number and formula for 2-Amino-3-(trifluoromethyl)pyridine?
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The CAS number for 2-Amino-3-(trifluoromethyl)pyridine is 183610-70-0, and its chemical formula is C6H5F3N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-3-(trifluoromethyl)pyridine with an assay of 97%. This product is suitable for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 2-Amino-3-(trifluoromethyl)pyridine be handled safely?
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2-Amino-3-(trifluoromethyl)pyridine is classified as Dangerous (GHS06). It is toxic if swallowed (H301), can cause an allergic skin reaction (H317), and causes serious eye irritation (H319). Handle with appropriate personal protective equipment (P280) and follow emergency procedures if exposed (P301+P310, P305+P351+P338).
How is 2-Amino-3-(trifluoromethyl)pyridine shipped and exported?
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This compound is classified under UN 2811, Class 6.1, Packing Group III, indicating it is a toxic solid. Tech Serve Solutions adheres to all regulations for the safe packaging, shipping, and export of hazardous chemicals.
How can I request a quote or sample of 2-Amino-3-(trifluoromethyl)pyridine?
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To request a quote or a sample of 2-Amino-3-(trifluoromethyl)pyridine, please contact our sales team through the website or by phone, providing your specific requirements.
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