(R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline
(R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline (CAS: 866081-62-1) is a chiral phosphine ligand with a molecular weight of 334.38 g/mol. This compound is highly valued for its efficacy in asymmetric synthesis, enabling high levels of enantiocontrol in various metal-catalyzed transformations. Its applications include 1,4-addition reactions and asymmetric hydrogenation, making it a key reagent for stereoselective synthesis in research and development.
- IUPAC
- (R) QuinoxP®
- Synonyms
- 866081-62-1C18H28N2P2(R) QuinoxP®

Asymmetric Synthesis
This ligand facilitates high enantioselectivity in metal-catalyzed reactions, crucial for the synthesis of chiral molecules.
Catalysis
It is employed as a chiral ligand in asymmetric hydrogenation and 1,4-addition reactions, enhancing stereocontrol.
Research and Development
Utilised in academic and industrial R&D for developing novel stereoselective synthetic routes.
| Molecular weight | 334.38 |
|---|---|
| Empirical formula | C18H28N2P2 |
| Assay | 97% |
| Application | Efficient ligand exhibiting high levels of enantiocontrol in synthetic transformations ranging from metal-catalyzed 1,4-addition of arylboronic acids to alkylative ring opening to asymmetric hydrogenation.1 |
| Melting point | 100-104 °C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline used for?
+
It is used as an efficient chiral ligand for asymmetric synthesis, particularly in metal-catalyzed 1,4-addition and asymmetric hydrogenation reactions, providing high enantiocontrol.
What are the CAS number and formula for (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline?
+
The CAS number is 866081-62-1 and the molecular formula is C18H28N2P2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product with an assay of 97%. It is suitable for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline be handled?
+
This compound is classified as Danger. It is harmful if swallowed, causes skin irritation, causes serious eye irritation, may cause respiratory irritation, and may cause long-lasting harmful effects to aquatic life. Handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, face shields, and gloves in a well-ventilated area. Avoid dust formation and inhalation.
Is (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline a controlled substance?
+
The provided data does not indicate that this compound is a controlled substance.
How is this chemical packed, shipped, and exported?
+
As a global supplier, Tech Serve Solutions ensures appropriate packaging for safe transit. This product is shipped and exported in compliance with international regulations for hazardous materials (UN 2811 6.1 / PGIII).
How can I request a sample or a quote?
+
Please contact our sales team through the website to request a sample or a quotation for (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis