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(R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline

CAS 866081-62-1C18H28N2P2Chemical Synthesis

(R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline (CAS: 866081-62-1) is a chiral phosphine ligand with a molecular weight of 334.38 g/mol. This compound is highly valued for its efficacy in asymmetric synthesis, enabling high levels of enantiocontrol in various metal-catalyzed transformations. Its applications include 1,4-addition reactions and asymmetric hydrogenation, making it a key reagent for stereoselective synthesis in research and development.

IUPAC
(R) QuinoxP®
Synonyms
866081-62-1C18H28N2P2(R) QuinoxP®
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(R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline (C18H28N2P2) — chemical structure, CAS 866081-62-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsOther Chiral LigandsQuinoxP* Ligands More...
01 /Applications

Asymmetric Synthesis

This ligand facilitates high enantioselectivity in metal-catalyzed reactions, crucial for the synthesis of chiral molecules.

Catalysis

It is employed as a chiral ligand in asymmetric hydrogenation and 1,4-addition reactions, enhancing stereocontrol.

Research and Development

Utilised in academic and industrial R&D for developing novel stereoselective synthetic routes.

02 /Properties
Molecular weight334.38
Empirical formulaC18H28N2P2
Assay97%
ApplicationEfficient ligand exhibiting high levels of enantiocontrol in synthetic transformations ranging from metal-catalyzed 1,4-addition of arylboronic acids to alkylative ring opening to asymmetric hydrogenation.1
Melting point100-104 °C
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H301Toxic if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation
  • H413May cause long-lasting harmful effects to aquatic life

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P301IF SWALLOWED
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Transport (UN / ADR)UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22-36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
866081-62-1
MDL number
MFCD10565649
PubChem substance
24884852
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline used for?

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It is used as an efficient chiral ligand for asymmetric synthesis, particularly in metal-catalyzed 1,4-addition and asymmetric hydrogenation reactions, providing high enantiocontrol.

What are the CAS number and formula for (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline?

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The CAS number is 866081-62-1 and the molecular formula is C18H28N2P2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product with an assay of 97%. It is suitable for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.

How should (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline be handled?

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This compound is classified as Danger. It is harmful if swallowed, causes skin irritation, causes serious eye irritation, may cause respiratory irritation, and may cause long-lasting harmful effects to aquatic life. Handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, face shields, and gloves in a well-ventilated area. Avoid dust formation and inhalation.

Is (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline a controlled substance?

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The provided data does not indicate that this compound is a controlled substance.

How is this chemical packed, shipped, and exported?

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As a global supplier, Tech Serve Solutions ensures appropriate packaging for safe transit. This product is shipped and exported in compliance with international regulations for hazardous materials (UN 2811 6.1 / PGIII).

How can I request a sample or a quote?

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Please contact our sales team through the website to request a sample or a quotation for (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline.

Need (R,R)-(–)-2,3-Bis(tert-butylmethylphosphino)quinoxaline in a specific grade or volume?