(R,R)-(+)-2-Amino-1,2-diphenylethanol
(R,R)-(+)-2-Amino-1,2-diphenylethanol (CAS 88082-66-0) is a chiral amino alcohol with a molecular weight of 213.28 g/mol. This compound is a valuable building block in organic synthesis, particularly for asymmetric synthesis. Its defined stereochemistry makes it useful in the preparation of enantiomerically pure target molecules, finding applications in research and development settings for pharmaceuticals and fine chemicals.
- Synonyms
- 88082-66-0, C6H5CH(NH2)CH(C6H5)OH
Chiral Auxiliary in Asymmetric Synthesis
This compound can serve as a chiral auxiliary, enabling the stereoselective synthesis of new chiral centres in organic molecules. Its specific stereochemistry influences the transition state of reactions, leading to the preferential formation of one enantiomer over the other.
Precursor for Chiral Ligands
The amino alcohol functionality allows for further derivatization, making it a useful precursor for the synthesis of chiral ligands. These ligands are critical components in asymmetric catalysis, facilitating enantioselective transformations.
Building Block for Pharmaceuticals
As an enantiomerically pure building block, it is employed in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs) where specific stereochemistry is crucial for biological activity.
Research and Development
Used in academic and industrial research labs for exploring new synthetic methodologies and developing novel chiral compounds with potential applications in various fields of chemistry.
| Molecular weight | 213.28 |
|---|---|
| Linear formula | C6H5CH(NH2)CH(C6H5)OH |
| Assay | ≥99.5% (HPLC) |
| Optical activity | [α]/D +124±3°, c = 0.87 in ethanol |
| Optical purity | enantiomeric excess: ≥99.0% (HPLC) |
| Storage temperature | 2-8°C |
| Melting point | 116-119 °C |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R,R)-(+)-2-Amino-1,2-diphenylethanol used for?
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(R,R)-(+)-2-Amino-1,2-diphenylethanol is primarily used as a chiral building block and auxiliary in asymmetric synthesis, and as a precursor for chiral ligands in catalysis. It is valuable in the research and development of enantiomerically pure compounds, including pharmaceutical intermediates.
What are the CAS number and formula for (R,R)-(+)-2-Amino-1,2-diphenylethanol?
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The CAS number is 88082-66-0, and its linear formula is C14H15NO, which can be represented as C6H5CH(NH2)CH(C6H5)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R,R)-(+)-2-Amino-1,2-diphenylethanol with an assay of ≥99.5% (HPLC) and an enantiomeric excess of ≥99.0% (HPLC). We do not represent this product as USP, EP, BP or any other pharmacopoeia grade.
What are the safety and handling recommendations for this compound?
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This compound is classified with GHS07 symbol and a 'Warning' signal word, with hazard statement H302 (Harmful if swallowed). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation when handling.
How is (R,R)-(+)-2-Amino-1,2-diphenylethanol typically packed and shipped?
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Products are packed according to industry best practices and regulatory requirements for safe transport. Tech Serve Solutions is experienced in exporting fine chemicals globally, ensuring compliance with international shipping regulations.
How can I request a sample or quote for (R,R)-(+)-2-Amino-1,2-diphenylethanol?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (88082-66-0).
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