trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid
trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid (CAS: 167690-53-1, C23H25NO4) is a valuable alicyclic amino acid derivative. Its structure incorporates the Fmoc protecting group, making it highly suitable for solid-phase peptide synthesis. This compound is predominantly utilised in chemical biology and organic synthesis for the construction of complex peptides and peptidomimetics, offering a unique cyclic scaffold. It is supplied by TSS with a minimum purity of 98.0% by HPLC.
- IUPAC
- N-Fmoc-tranexamic acid
- Synonyms
- N-Fmoc-tranexamic acid

Peptide Synthesis
This Fmoc-protected amino acid is instrumental in the synthesis of peptides, particularly on solid supports. Its alicyclic structure introduces conformational constraints into the growing peptide chain.
Chemical Biology Research
It serves as a building block for creating modified peptides and peptidomimetics. These molecules are used to study biological processes and develop new therapeutic agents.
Organic Synthesis
The compound is employed in general organic synthesis for the introduction of the trans-4-(aminomethyl)cyclohexanecarboxylic acid moiety into target molecules, often requiring the protection afforded by the Fmoc group.
Unnatural Amino Acid Libraries
It is a key component in the design and synthesis of libraries containing unnatural amino acids, expanding the chemical space accessible for drug discovery and materials science.
| Molecular weight | 379.45 |
|---|---|
| Empirical formula | C23H25NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid used for?
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trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid is primarily used in solid-phase peptide synthesis, chemical biology research, and organic synthesis as a building block for creating modified peptides, peptidomimetics, and unnatural amino acid derivatives.
What are the CAS number and formula for trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid?
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The CAS number is 167690-53-1 and the empirical formula (Hill notation) is C23H25NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid with an assay of ≥98.0% determined by HPLC. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for this compound?
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Handling this compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The WGK (Germany) is 3, indicating a high hazard.
How is trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid shipped and exported?
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This chemical is typically stored at 2-8°C. As a global supplier, TSS has extensive experience in exporting chemicals worldwide, adhering to all relevant shipping and customs regulations.
How can I request a quote or sample?
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To request a quote or a sample of trans-4-(Fmoc-aminomethyl)cyclohexanecarboxylic acid, please contact our sales department through the TSS website or by calling us directly.
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