(R)-Boc-4-(trifluoromethyl)-β-Phe-OH
(R)-Boc-4-(trifluoromethyl)-β-Phe-OH (CAS: 501015-19-6), with the molecular formula C15H18F3NO4 and a molecular weight of 333.30 g/mol, is a protected unnatural beta-amino acid derivative. It is a valuable building block in synthetic organic chemistry, particularly in the fields of peptide chemistry and chemical biology, enabling the incorporation of unique structural motifs into peptides and small molecules. Its trifluoromethyl group offers distinctive electronic and lipophilic properties.
- IUPAC
- (R)-3-(Boc-amino)-3-[4-(trifluoromethyl)phenyl]propionic acid,Boc-4-(trifluoromethyl)-L-β-phenylalanine
- Synonyms
- (R)-3-(Boc-amino)-3-[4-(trifluoromethyl)phenyl]propionic acidBoc-4-(trifluoromethyl)-L-β-phenylalanine
Peptide Synthesis
Serves as a non-canonical amino acid for incorporation into peptides, allowing for the exploration of modified peptide structures with altered conformational stability or biological activity.
Medicinal Chemistry
Utilised as a building block in the synthesis of novel pharmaceutical candidates, where the trifluoromethyl group can enhance metabolic stability or binding affinity.
Chemical Biology Research
Employed in the design and synthesis of probes or modified biomolecules for studying biological processes at the molecular level.
Organic Synthesis
A versatile intermediate for creating complex organic molecules, leveraging the protected amine and carboxylic acid functionalities alongside the trifluoromethylphenyl moiety.
| Molecular weight | 333.30 |
|---|---|
| Empirical formula | C15H18F3NO4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Boc-4-(trifluoromethyl)-β-Phe-OH used for?
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(R)-Boc-4-(trifluoromethyl)-β-Phe-OH is primarily used as a building block in peptide synthesis, medicinal chemistry, and organic synthesis due to its unnatural beta-amino acid structure featuring a trifluoromethylphenyl group.
What is the CAS number and formula for (R)-Boc-4-(trifluoromethyl)-β-Phe-OH?
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The CAS number is 501015-19-6 and the empirical formula is C15H18F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Boc-4-(trifluoromethyl)-β-Phe-OH with an assay of ≥98.0% determined by HPLC. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for this compound?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3, indicating a high hazard to water.
Can Tech Serve Solutions export (R)-Boc-4-(trifluoromethyl)-β-Phe-OH?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (R)-Boc-4-(trifluoromethyl)-β-Phe-OH.
How can I request a quote or sample?
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Please contact our sales team directly via phone or email to request a quote or to arrange for a sample of (R)-Boc-4-(trifluoromethyl)-β-Phe-OH.
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