(R)-Boc-4-chloro-β-Phe-OH
(R)-Boc-4-chloro-β-Phe-OH (CAS: 479064-93-2) is a chiral, non-proteinogenic beta-amino acid derivative. With the molecular formula C14H18ClNO4 and a molecular weight of 299.75 g/mol, this compound is essential for advancing research in chemical biology and peptide chemistry. It serves as a valuable building block in the synthesis of complex molecules and unnatural peptide structures, enabling novel biochemical investigations and drug discovery efforts.
- IUPAC
- (R)-3-(Boc-amino)-3-(4-chlorophenyl)propionic acid,Boc-4-chloro-L-β-phenylalanine

Peptide Synthesis
Incorporated into peptide chains, this unnatural amino acid derivative allows for the creation of peptidomimetics and modified peptides with altered biological activities or stability profiles. Its specific chirality and functional groups are critical for precise structural control.
Chemical Biology Research
Utilised as a tool compound in chemical biology to probe protein-ligand interactions or to develop novel biomolecular probes. Its unique structure can confer specific properties to the molecules it is incorporated into.
Organic Synthesis Intermediate
Serves as a versatile intermediate in the synthesis of complex organic molecules, particularly those requiring a chiral beta-amino acid core. The Boc-protecting group and chloro-substituent offer strategic points for further chemical modification.
| Molecular weight | 299.75 |
|---|---|
| Empirical formula | C14H18ClNO4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Boc-4-chloro-β-Phe-OH used for?
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(R)-Boc-4-chloro-β-Phe-OH is primarily used as a building block in peptide synthesis, chemical biology research, and organic synthesis. It is particularly valuable for creating unnatural peptides, peptidomimetics, and complex chiral molecules.
What is the CAS number and molecular formula for this compound?
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The CAS number is 479064-93-2, and the molecular formula is C14H18ClNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Boc-4-chloro-β-Phe-OH with an assay of ≥98.0% (HPLC). This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should (R)-Boc-4-chloro-β-Phe-OH be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3, indicating potential environmental hazards.
Is this product packed and shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (R)-Boc-4-chloro-β-Phe-OH, serving customers worldwide.
How can I request a quote or sample?
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To request a quote or a sample of (R)-Boc-4-chloro-β-Phe-OH, please contact our sales department through the TSS website or by phone.
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