(R)-Boc-4-chloro-β-Homophe-OH
(R)-Boc-4-chloro-β-Homophe-OH (CAS: 218608-96-9) is a chiral unnatural amino acid derivative with the molecular formula C15H20ClNO4 and a molecular weight of 313.78 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly in peptide chemistry and chemical biology. Its structure makes it useful for the development of novel peptides and complex molecules where specific stereochemistry is required.
- IUPAC
- (R)-3-(Boc-amino)-4-(4-chlorophenyl)butyric acid,Boc-4-chloro-D-β-homophenylalanine
- Synonyms
- (R)-3-(Boc-amino)-4-(4-chlorophenyl)butyric acidBoc-4-chloro-D-β-homophenylalanine

Peptide Synthesis
This unnatural amino acid derivative is employed as a building block in the synthesis of modified peptides. It allows for the introduction of specific structural features and chirality into peptide chains, enabling the exploration of structure-activity relationships.
Chemical Biology Research
Used in chemical biology to construct probes or modified biomolecules. Its unique structure can be incorporated into biological systems to study protein function, interactions, or pathways.
Organic Synthesis Intermediate
Serves as a versatile intermediate in complex organic synthesis. The Boc-protected amine and the chloro-substituted phenyl group offer multiple functionalization points for further chemical transformations.
| Molecular weight | 313.78 |
|---|---|
| Empirical formula | C15H20ClNO4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Boc-4-chloro-β-Homophe-OH used for?
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(R)-Boc-4-chloro-β-Homophe-OH is primarily used as a building block in peptide synthesis, chemical biology research, and general organic synthesis due to its unnatural amino acid structure and chirality.
What is the CAS number and formula for (R)-Boc-4-chloro-β-Homophe-OH?
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The CAS number is 218608-96-9 and the empirical formula (Hill notation) is C15H20ClNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Boc-4-chloro-β-Homophe-OH with an assay of ≥98.0% (HPLC). This product is supplied for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should (R)-Boc-4-chloro-β-Homophe-OH be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK 2 in Germany, indicating it is hazardous to water.
Is this chemical suitable for pharmaceutical manufacturing?
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This compound is supplied for research and development. It is not supplied in USP, BP, or EP grade, and its suitability for pharmaceutical manufacturing would require further validation and regulatory compliance.
How is (R)-Boc-4-chloro-β-Homophe-OH packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, ensuring appropriate packaging and compliance with international shipping regulations for laboratory reagents.
How can I request a quote or sample?
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Please contact our sales team via the website or direct inquiry to request a quote or sample of (R)-Boc-4-chloro-β-Homophe-OH.
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