(R)-(−)-3-Amino-1-Boc-piperidine
(R)-(−)-3-Amino-1-Boc-piperidine (CAS: 188111-79-7; Formula: C10H20N2O2; Mol. Wt.: 200.28) is a chiral heterocyclic building block. This piperidine derivative is primarily employed in asymmetric synthesis and general chemical synthesis. Its specific stereochemistry makes it a valuable intermediate for creating complex molecules with defined chirality, particularly in pharmaceutical and agrochemical research and development.
- IUPAC
- (R)-1-Boc-3-piperidinamine,tert-Butyl (R)-3-amino-1-piperidinecarboxylate
- Synonyms
- tert-Butyl (R)-3-amino-1-piperidinecarboxylate
Chiral Synthesis Intermediate
Serves as a key chiral building block for introducing a stereodefined piperidine moiety into target molecules. Its (R)-configuration is crucial for developing enantiomerically pure active pharmaceutical ingredients (APIs) and other complex organic compounds.
Asymmetric Synthesis
Utilised in asymmetric synthesis strategies where precise control over stereochemistry is paramount. It facilitates the construction of chiral centres and is valuable in the synthesis of enantiopure pharmaceuticals and fine chemicals.
Heterocyclic Chemistry
As a functionalised piperidine, it is a versatile synthon in heterocyclic chemistry. It allows for further functionalization and elaboration, leading to diverse nitrogen-containing heterocyclic structures relevant to medicinal chemistry.
| Molecular weight | 200.28 |
|---|---|
| Empirical formula | C10H20N2O2 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]/D -28.5±2°, c = 1 in DMF |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-3-Amino-1-Boc-piperidine used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and general chemical synthesis, particularly for introducing stereodefined piperidine structures in the development of pharmaceuticals and fine chemicals.
What are the CAS number and chemical formula for (R)-(−)-3-Amino-1-Boc-piperidine?
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The CAS number is 188111-79-7 and the empirical formula is C10H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-3-Amino-1-Boc-piperidine with a minimum assay of ≥98.0% (TLC). This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should (R)-(−)-3-Amino-1-Boc-piperidine be handled?
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This compound is classified as a Warning substance (GHS07) and may cause harm if swallowed, skin irritation, serious eye irritation, and respiratory irritation (H302-H315-H319-H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Always consult the Safety Data Sheet (SDS) before handling.
How is (R)-(−)-3-Amino-1-Boc-piperidine packed and shipped?
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Tech Serve Solutions offers various packaging options suitable for fine chemicals, ensuring product integrity during storage and transport. We export globally, adhering to all relevant shipping regulations for chemical products.
How can I request a sample or quote?
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To request a sample or a quotation for (R)-(−)-3-Amino-1-Boc-piperidine, please visit the product page on our website or contact our sales team directly with your requirements.
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