(R)-(−)-3-Chloro-1,2-propanediol
(R)-(−)-3-Chloro-1,2-propanediol (CAS: 57090-45-6) is a chiral organic compound with the linear formula ClCH2CH(OH)CH2OH and a molecular weight of 110.54 g/mol. It serves as a valuable chiral building block and intermediate in asymmetric synthesis and organic chemical synthesis. This polyol derivative is crucial for creating complex stereospecific molecules in various chemical research and development applications.
- IUPAC
- (R)-α-Glycerol chlorohydrin
- Synonyms
- ClCH2CH(OH)CH2OH(R)-alpha-Glycerol chlorohydrin
Asymmetric Synthesis
This compound is a key chiral building block utilized in asymmetric synthesis to construct enantiomerically pure molecules. Its defined stereochemistry allows for stereoselective reactions in the development of complex organic compounds.
Organic Synthesis Intermediate
As a versatile intermediate, (R)-(−)-3-Chloro-1,2-propanediol facilitates the synthesis of various organic compounds. It is employed in multi-step synthetic pathways where precise structural control is required.
Chiral Pool Synthesis
It functions as a chiral synthon, enabling the introduction of chirality into target molecules. This is particularly important in the synthesis of pharmaceuticals and other biologically active compounds.
| Molecular weight | 110.54 |
|---|---|
| Linear formula | ClCH2CH(OH)CH2OH |
| Assay | 97% |
| Boiling point | 213 °C(lit.) |
| Density | 1.321 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.48(lit.) |
| Optical activity | [α]20/D −1°, neat |
| Optical purity | ee: 98% (GLC) |
| Vapour pressure | 0.04 mmHg (25 °C) |
Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 135 °C / 275 °F |
| Transport (UN / ADR) | UN 2689 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-41 |
| Safety statements (S) | 26-28-39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-3-Chloro-1,2-propanediol used for?
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(R)-(−)-3-Chloro-1,2-propanediol is primarily used as a chiral building block and intermediate in asymmetric synthesis and general organic chemical synthesis.
What are the CAS number and formula for (R)-(−)-3-Chloro-1,2-propanediol?
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The CAS number for (R)-(−)-3-Chloro-1,2-propanediol is 57090-45-6 and its linear formula is ClCH2CH(OH)CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-3-Chloro-1,2-propanediol with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should (R)-(−)-3-Chloro-1,2-propanediol be handled safely?
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This compound is classified as Dangerous (GHS05, GHS06) with a Signal Word of Danger. It carries Hazard Statements H301 (Toxic if swallowed) and H318 (Causes serious eye damage). Appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves, should be worn. Refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (R)-(−)-3-Chloro-1,2-propanediol.
How can I request a sample or a quote?
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To request a sample or obtain a quote for (R)-(−)-3-Chloro-1,2-propanediol, please contact our sales department through the website or by phone.
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