(R)-(−)-3-Fluoropyrrolidine hydrochloride
(R)-(−)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-55-8) is a chiral fluorinated heterocyclic building block with a molecular weight of 125.57 g/mol. It is primarily utilised in asymmetric synthesis and chemical research. The compound's structure makes it a valuable intermediate for developing complex organic molecules, particularly in pharmaceutical research where fluorinated pyrrolidine motifs are often incorporated to modulate drug properties. Available at 97% purity.
Pharmaceutical Intermediate
This fluorinated pyrrolidine derivative serves as a key chiral building block in the synthesis of pharmacologically active compounds. Its structure is relevant for developing inhibitors, such as dipeptidyl peptidase IV inhibitors, where the fluorine atom can influence binding affinity and metabolic stability.
Asymmetric Synthesis
As a chiral compound, (R)-(−)-3-Fluoropyrrolidine hydrochloride is employed in asymmetric synthesis to introduce stereochemical control. It facilitates the creation of enantiomerically pure target molecules, which is critical in the development of modern pharmaceuticals and fine chemicals.
Organic Synthesis Reagent
This compound functions as a versatile reagent in general organic synthesis. Its heterocyclic and fluorinated nature offers unique reactivity and structural motifs for chemists exploring novel molecular architectures and synthetic pathways.
| Molecular weight | 125.57 |
|---|---|
| Empirical formula | C4H9ClFN |
| Assay | 97% |
| Optical activity | [α]20/D -8.0°, c = 4 in methanol |
| Application | The derived amide acts as an inhibitor of dipeptidyl peptidase IV.1 |
| Melting point | 179-186 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-3-Fluoropyrrolidine hydrochloride used for?
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It is used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals, including dipeptidyl peptidase IV inhibitors.
What is the CAS number and formula for (R)-(−)-3-Fluoropyrrolidine hydrochloride?
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The CAS number is 136725-55-8 and the empirical formula is C4H9ClFN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-3-Fluoropyrrolidine hydrochloride at a purity of 97%. This product is intended for research and chemical synthesis use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should (R)-(−)-3-Fluoropyrrolidine hydrochloride be handled safely?
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This compound is classified as a Warning with hazards H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent), should be used. Ensure adequate ventilation.
Is (R)-(−)-3-Fluoropyrrolidine hydrochloride a controlled substance?
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The provided data does not indicate that (R)-(−)-3-Fluoropyrrolidine hydrochloride is a controlled substance.
How can I request a sample or quote for (R)-(−)-3-Fluoropyrrolidine hydrochloride?
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Please contact our sales team via the website or direct email to request a sample or a quotation for (R)-(−)-3-Fluoropyrrolidine hydrochloride.
How is (R)-(−)-3-Fluoropyrrolidine hydrochloride packed and exported?
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Tech Serve Solutions exports fine chemicals globally. Products are carefully packed according to international shipping regulations to ensure safe transit and compliance. Specific packing details can be provided upon request.
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