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(R)-(−)-2-Amino-1-propanol

CAS 35320-23-1CH3CH(NH2)CH2OHChemical Synthesis

(R)-(−)-2-Amino-1-propanol (CAS: 35320-23-1), with the molecular formula CH3CH(NH2)CH2OH and a molecular weight of 75.11 g/mol, is a chiral amino alcohol. This optically active compound is valuable in asymmetric synthesis. Its specific rotation ([α]20/D −22±2°) indicates its R configuration, making it a key building block for stereoselective chemical transformations in research and development.

IUPAC
D-Alaninol
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(R)-(−)-2-Amino-1-propanol (CH3CH(NH2)CH2OH) — chemical structure, CAS 35320-23-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks
01 /Applications

Chiral Building Block

(R)-(−)-2-Amino-1-propanol serves as a crucial chiral synthon. Its stereogenic centre allows for the introduction of specific chirality in target molecules during complex organic synthesis.

Asymmetric Synthesis

This amino alcohol is employed in asymmetric synthesis to create enantiomerically pure compounds. It is particularly useful in developing chiral ligands or auxiliaries for stereoselective reactions.

Pharmaceutical Intermediate

As an organic building block, it can be a precursor in the synthesis of pharmaceutically active ingredients where specific stereochemistry is essential for efficacy and safety.

02 /Properties
Molecular weight75.11
Linear formulaCH3CH(NH2)CH2OH
Assay≥98.5% (sum of enantiomers, GC)
Boiling point166-168 °C(lit.)
Density0.963 g/mL at 20 °C(lit.)
Refractive indexn20/D 1.4493(lit.)n20/D 1.450
Optical activity[α]20/D −22±2°, c = 2% in ethanol
Optical purityenantiomeric ratio: ≥99.5:0.5 (HPLC)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point83 °C / 181.4 °F
Transport (UN / ADR)UN 2735PSN1 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
35320-23-1
MDL number
MFCD00064413
PubChem substance
24857919
Beilstein registry
1718866
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(−)-2-Amino-1-propanol used for?

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(R)-(−)-2-Amino-1-propanol is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the production of complex organic molecules, including potential pharmaceutical compounds.

What are the CAS number and molecular formula of (R)-(−)-2-Amino-1-propanol?

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The CAS number for (R)-(−)-2-Amino-1-propanol is 35320-23-1, and its molecular formula is CH3CH(NH2)CH2OH.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-(−)-2-Amino-1-propanol with an assay of ≥98.5% (sum of enantiomers, GC). TSS does not represent this product as USP, BP, or EP grade unless explicitly stated otherwise in the product data.

How should (R)-(−)-2-Amino-1-propanol be handled safely?

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This compound causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, is mandatory. Handle in a well-ventilated area, avoiding contact with skin, eyes, and clothing.

Is (R)-(−)-2-Amino-1-propanol a controlled substance?

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The provided data does not indicate that (R)-(−)-2-Amino-1-propanol is a controlled substance.

How is (R)-(−)-2-Amino-1-propanol packaged and shipped?

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As a global supplier, Tech Serve Solutions exports (R)-(−)-2-Amino-1-propanol, adhering to all necessary shipping and handling regulations for hazardous materials, including UN 2735 classification.

How can I request a quote or sample?

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To request a quote or sample of (R)-(−)-2-Amino-1-propanol, please contact the Tech Serve Solutions sales department through our website or by phone.

Need (R)-(−)-2-Amino-1-propanol in a specific grade or volume?