(R)-(−)-2-Amino-1-phenylethanol
(R)-(−)-2-Amino-1-phenylethanol (CAS: 2549-14-6), with the molecular formula H2NCH2CH(C6H5)OH and a molecular weight of 137.18 g/mol, is a valuable chiral amino alcohol. This optically active compound, exhibiting specific rotation [α]22/D −39°, is primarily utilised as a chiral building block in asymmetric synthesis and complex organic chemical synthesis. Its structure makes it a versatile intermediate for the development of advanced chemical entities.
- IUPAC
- (R)-α-(Aminomethyl)benzyl alcohol
- Synonyms
- (R)-α-(Aminomethyl)benzyl alcohol
Chiral Building Block in Asymmetric Synthesis
This enantiomerically pure amino alcohol serves as a crucial precursor in stereoselective synthetic routes. Its defined stereochemistry allows for the introduction of chirality in target molecules, essential for pharmaceuticals and fine chemicals.
Intermediate in Organic Synthesis
The dual functionality of the amino and hydroxyl groups, coupled with its chiral centre, makes (R)-(−)-2-Amino-1-phenylethanol a versatile intermediate. It is employed in multi-step syntheses to construct complex organic structures with high stereochemical control.
Precursor for Pharmaceutical Intermediates
As a chiral amine alcohol, it is frequently used in the synthesis of active pharmaceutical ingredients (APIs) and their advanced intermediates, where specific stereoisomers are critical for biological activity and safety.
| Molecular weight | 137.18 |
|---|---|
| Linear formula | H2NCH2CH(C6H5)OH |
| Assay | 97% |
| Optical activity | [α]22/D −39°, c = 2 in ethanol |
| Melting point | 59-65 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3259 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2-Amino-1-phenylethanol primarily used for?
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(R)-(−)-2-Amino-1-phenylethanol is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in complex organic chemical synthesis, particularly for pharmaceuticals.
What is the CAS number and molecular formula for (R)-(−)-2-Amino-1-phenylethanol?
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The CAS number is 2549-14-6, and the molecular formula is H2NCH2CH(C6H5)OH.
What grade and purity does Tech Serve Solutions supply for (R)-(−)-2-Amino-1-phenylethanol?
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Tech Serve Solutions supplies (R)-(−)-2-Amino-1-phenylethanol with an assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety hazards associated with (R)-(−)-2-Amino-1-phenylethanol?
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(R)-(−)-2-Amino-1-phenylethanol is classified as Danger. It is harmful if swallowed (H302) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, must be used.
How is (R)-(−)-2-Amino-1-phenylethanol packed and exported?
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This chemical is packed and shipped in accordance with UN 3259 8/PG 3 regulations, ensuring safe handling during transport and export.
How can I request a sample or a quote for (R)-(−)-2-Amino-1-phenylethanol?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team directly through our website or by phone, providing the product name and CAS number (2549-14-6).
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