Pyrimethamine
Pyrimethamine (CAS: 58-14-0; Formula: C12H13ClN4) is a chemical compound with a molecular weight of 248.71 g/mol. It functions as an inhibitor of dihydrofolate reductase. Primarily recognised for its antimalarial and antiparasitic properties, it is a valuable agent in pharmaceutical research and synthesis. Pyrimethamine is also utilised in cell biology studies and as a building block in chemical synthesis, particularly for heterocyclic compounds.
- IUPAC
- 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) due to its specific biological activity. Its role as a dihydrofolate reductase inhibitor makes it a key component in the development of therapeutic agents.
Cell Biology Research
Employed in laboratory settings to investigate cellular processes, particularly those involving folate metabolism. It serves as a tool compound for studying drug resistance mechanisms and cell growth inhibition.
Chemical Synthesis
Acts as a versatile building block for the creation of complex organic molecules, especially nitrogen-containing heterocycles. Its structure lends itself to further derivatisation in synthetic chemistry.
| Molecular weight | 248.71 |
|---|---|
| Empirical formula | C12H13ClN4 |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CYP2C9(1559), DHFRP1(573971)rat ... Dhfr(24312) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pyrimethamine used for?
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Pyrimethamine is primarily used as an antimalarial and antiparasitic agent, functioning as a dihydrofolate reductase inhibitor. It is also used in cell biology research and as a building block in chemical synthesis.
What are the CAS number and formula for Pyrimethamine?
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The CAS number for Pyrimethamine is 58-14-0, and its molecular formula is C12H13ClN4.
What grade and purity does Tech Serve Solutions supply for Pyrimethamine?
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Tech Serve Solutions supplies Pyrimethamine typically as a research or technical grade material. We do not represent this product as USP, BP, or EP grade unless explicitly stated otherwise in the product specifications.
What are the safety and handling considerations for Pyrimethamine?
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Pyrimethamine is classified as harmful if swallowed (H302). Appropriate personal protective equipment, including a dust mask (N95 US type), eyeshields, faceshields, and gloves, should be used when handling this compound.
Is Pyrimethamine a controlled substance?
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The provided data does not indicate that Pyrimethamine is a controlled substance. However, users should always verify current local regulations.
How is Pyrimethamine packed, shipped, and exported?
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Pyrimethamine is carefully packed to ensure integrity during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Pyrimethamine?
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To request a sample or a quotation for Pyrimethamine, please contact our sales team through the website or direct contact information provided.
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