Pyrimidine
Pyrimidine (CAS: 289-95-2, C4H4N2, MW: 80.09 g/mol) is a foundational heterocyclic organic compound. Its structure is integral to nucleic acids and various biologically active molecules. Pyrimidine serves as a key building block in chemical synthesis, particularly for developing pharmaceuticals and agrochemicals. It is also employed in research to study biochemical pathways and molecular interactions, making it a valuable reagent for synthetic and medicinal chemists.

Chemical Synthesis Building Block
Pyrimidine is a crucial heterocyclic building block in organic synthesis. It is widely used in the preparation of more complex molecules, including pharmaceutical intermediates and agrochemical active ingredients.
Biochemical Research
This compound has been utilised in research to quantitatively assess pyrimidine/purine asymmetry. It also aids in studying the photoinduced ion chemistry of halogenated pyrimidines, relevant to radiosensitizing agents.
Medicinal Chemistry Intermediate
As a core structure in many biologically significant compounds, pyrimidine is an important intermediate for medicinal chemists exploring novel therapeutic agents.
| Molecular weight | 80.09 |
|---|---|
| Empirical formula | C4H4N2 |
| Assay | ≥98.0% |
| Boiling point | 123-124 °C(lit.) |
| Density | 1.016 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.504(lit.) |
| Solubility | H2O: solublealcohols: solublediethyl ether: soluble |
| Melting point | 19-22 °C(lit.) |
| Application | Pyrimidine was used to assess the extent of pyrimidine/purine asymmetry quantitatively1. It was also used to study the photoinduced ion chemistry of the halogenated pyrimidines, a class of prototype radiosensitizing molecules2. |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 34 °C / 93.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
| Safety statements (S) | 23-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pyrimidine used for?
+
Pyrimidine is used as a chemical synthesis building block, particularly in the development of pharmaceuticals and agrochemicals. It also features in biochemical research, for instance, in studying pyrimidine/purine asymmetry and the photoinduced ion chemistry of radiosensitizing molecules.
What is the CAS number and molecular formula for Pyrimidine?
+
The CAS number for Pyrimidine is 289-95-2, and its molecular formula is C4H4N2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Pyrimidine with an assay of ≥98.0%. This is a technical/research grade, and we do not represent it as USP, BP, or EP grade.
How should Pyrimidine be handled safely?
+
Pyrimidine is a flammable liquid and vapour (H226). Handle with appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves. Ensure adequate ventilation and avoid ignition sources.
Can Pyrimidine be exported by Tech Serve Solutions?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Pyrimidine, adhering to all relevant shipping regulations (UN 1993, Class 3, PGIII).
How can I request a sample or quote for Pyrimidine?
+
Please contact our sales team via the website or direct email to request a sample or a formal quotation for Pyrimidine.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis