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Pyrimidine

CAS 289-95-2C4H4N2Chemical Synthesis

Pyrimidine (CAS: 289-95-2, C4H4N2, MW: 80.09 g/mol) is a foundational heterocyclic organic compound. Its structure is integral to nucleic acids and various biologically active molecules. Pyrimidine serves as a key building block in chemical synthesis, particularly for developing pharmaceuticals and agrochemicals. It is also employed in research to study biochemical pathways and molecular interactions, making it a valuable reagent for synthetic and medicinal chemists.

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Pyrimidine (C4H4N2) — chemical structure, CAS 289-95-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC4 to C5Chemical SynthesisHeterocyclic Building BlocksPyrimidines
01 /Applications

Chemical Synthesis Building Block

Pyrimidine is a crucial heterocyclic building block in organic synthesis. It is widely used in the preparation of more complex molecules, including pharmaceutical intermediates and agrochemical active ingredients.

Biochemical Research

This compound has been utilised in research to quantitatively assess pyrimidine/purine asymmetry. It also aids in studying the photoinduced ion chemistry of halogenated pyrimidines, relevant to radiosensitizing agents.

Medicinal Chemistry Intermediate

As a core structure in many biologically significant compounds, pyrimidine is an important intermediate for medicinal chemists exploring novel therapeutic agents.

02 /Properties
Molecular weight80.09
Empirical formulaC4H4N2
Assay≥98.0%
Boiling point123-124 °C(lit.)
Density1.016 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.504(lit.)
SolubilityH2O: solublealcohols: solublediethyl ether: soluble
Melting point19-22 °C(lit.)
ApplicationPyrimidine was used to assess the extent of pyrimidine/purine asymmetry quantitatively1. It was also used to study the photoinduced ion chemistry of the halogenated pyrimidines, a class of prototype radiosensitizing molecules2.
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
Warning

Hazard statements

  • H226Flammable liquid and vapour
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point34 °C / 93.2 °F
Transport (UN / ADR)UN 1993C 3 / PGIII
Water hazard class (WGK, DE)3
Risk statements (R)10
Safety statements (S)23-24/25

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
289-95-2
MDL number
MFCD00006059
PubChem substance
24848029
Beilstein registry
103894
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Pyrimidine used for?

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Pyrimidine is used as a chemical synthesis building block, particularly in the development of pharmaceuticals and agrochemicals. It also features in biochemical research, for instance, in studying pyrimidine/purine asymmetry and the photoinduced ion chemistry of radiosensitizing molecules.

What is the CAS number and molecular formula for Pyrimidine?

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The CAS number for Pyrimidine is 289-95-2, and its molecular formula is C4H4N2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Pyrimidine with an assay of ≥98.0%. This is a technical/research grade, and we do not represent it as USP, BP, or EP grade.

How should Pyrimidine be handled safely?

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Pyrimidine is a flammable liquid and vapour (H226). Handle with appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves. Ensure adequate ventilation and avoid ignition sources.

Can Pyrimidine be exported by Tech Serve Solutions?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Pyrimidine, adhering to all relevant shipping regulations (UN 1993, Class 3, PGIII).

How can I request a sample or quote for Pyrimidine?

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Please contact our sales team via the website or direct email to request a sample or a formal quotation for Pyrimidine.

Need Pyrimidine in a specific grade or volume?