3,4-Difluorothiophenol
3,4-Difluorothiophenol (CAS: 60811-24-7), with the molecular formula C6H3F2SH and a molecular weight of 146.16 g/mol, is a valuable organic synthesis intermediate. This fluorinated aromatic thiol serves as a key building block in the development of diverse chemical compounds, particularly within pharmaceutical and agrochemical research. Its unique structure allows for specific chemical transformations, making it an important reagent for advanced organic synthesis applications.
- Synonyms
- F2C6H3SH3,4-Difluorobenzenethiol
Pharmaceutical Intermediate Synthesis
3,4-Difluorothiophenol is employed as a crucial intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its fluorinated aromatic structure can impart desirable pharmacokinetic properties to drug candidates.
Agrochemical Development
This compound serves as a building block for novel agrochemicals, contributing to the development of new pesticides and herbicides. The introduction of fluorine atoms can enhance biological activity and stability.
Materials Science Research
It can be utilised in the synthesis of advanced materials where specific electronic or physical properties are desired. The thiol group offers a reactive handle for polymerisation or surface modification.
Organic Synthesis Reagent
As a versatile organofluorine compound, 3,4-Difluorothiophenol is a useful reagent in general organic synthesis for introducing the difluorophenylthio moiety into complex molecules.
| Molecular weight | 146.16 |
|---|---|
| Linear formula | F2C6H3SH |
| Assay | 96% |
| Boiling point | 169-170 °C(lit.) |
| Density | 1.323 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.528(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 48 °C / 118.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Difluorothiophenol used for?
+
3,4-Difluorothiophenol is primarily used as an intermediate and building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and molecular formula for 3,4-Difluorothiophenol?
+
The CAS number is 60811-24-7 and the linear molecular formula is F2C6H3SH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3,4-Difluorothiophenol with an assay of 96%. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should 3,4-Difluorothiophenol be handled safely?
+
3,4-Difluorothiophenol is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Keep away from heat and open flames.
Is 3,4-Difluorothiophenol a controlled substance?
+
Based on the provided data, 3,4-Difluorothiophenol is not listed as a controlled substance.
How is 3,4-Difluorothiophenol packed and shipped?
+
3,4-Difluorothiophenol is packed according to safety regulations for flammable liquids and hazardous materials. It is available for export globally by Tech Serve Solutions.
How can I request a quote or sample for 3,4-Difluorothiophenol?
+
To request a quote or sample, please contact our sales department through the website or by phone, referencing the product name and CAS number.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis