3,4-Difluorophenylmagnesium bromide solution
3,4-Difluorophenylmagnesium bromide solution (CAS: 90897-92-0) is an organometallic reagent. This Grignard reagent, with a molecular weight of 217.29 g/mol, is supplied at a concentration of 0.5 M in Tetrahydrofuran (THF). It is a valuable building block in organic synthesis, particularly for introducing the 3,4-difluorophenyl moiety into complex molecules. Its reactivity makes it suitable for various carbon-carbon bond-forming reactions.
- Synonyms
- F2C6H3MgBr
Organic Synthesis Intermediate
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. The 3,4-difluorophenyl group can be incorporated into target molecules via reactions with electrophiles.
Grignard Reagent Reactions
Participates in nucleophilic addition reactions with aldehydes, ketones, esters, and nitriles to form new carbon-carbon bonds. This enables the construction of more complex fluorinated organic structures.
Organometallic Chemistry
Serves as a precursor in the preparation of other organometallic compounds or for functionalising various substrates in academic and industrial research settings.
| Molecular weight | 217.29 |
|---|---|
| Linear formula | F2C6H3MgBr |
| Boiling point | 65 °C |
| Density | 0.965 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Difluorophenylmagnesium bromide solution used for?
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3,4-Difluorophenylmagnesium bromide solution is primarily used as a reagent in organic synthesis, particularly for introducing the 3,4-difluorophenyl group into molecules during the creation of pharmaceuticals, agrochemicals, and other complex organic compounds.
What are the CAS number and formula for 3,4-Difluorophenylmagnesium bromide solution?
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The CAS number is 90897-92-0 and the linear formula is F2C6H3MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Difluorophenylmagnesium bromide solution at a concentration of 0.5 M in THF. We do not represent this product as USP, BP, or EP grade; it is supplied for research and chemical synthesis purposes.
How should 3,4-Difluorophenylmagnesium bromide solution be handled safely?
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This solution is highly flammable (H225) and can cause serious eye irritation (H319) and respiratory irritation (H335). It is also suspected of causing cancer (H351) and may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Store refrigerated at 2-8°C.
How is 3,4-Difluorophenylmagnesium bromide solution packed and shipped?
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As per UN 2924 standards, this product is classified as hazardous, packed in accordance with regulations for flammable liquids and corrosive solids, and can be exported globally by Tech Serve Solutions.
How can I request a sample or quote for 3,4-Difluorophenylmagnesium bromide solution?
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To request a sample or obtain a quote, please contact our sales team through the website or by calling our office, specifying the product name and CAS number.
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