Potassium tert-butoxide
Potassium tert-butoxide (CAS: 865-47-4) is a strong, non-nucleophilic base widely employed in organic synthesis. Its linear formula is (CH3)3COK, and it has a molecular weight of 112.21 g/mol. This compound is crucial for various deprotonation reactions and elimination processes. Supplied by TSS as a reagent with high purity, it serves as a valuable tool in research and industrial chemical applications, facilitating complex organic transformations.
- IUPAC
- Potassium tert-butylate,Potassium t-butoxide
- Synonyms
- Potassium tert-butylatePotassium t-butoxide

Organic Synthesis Reagent
Potassium tert-butoxide is extensively used as a strong base in organic synthesis, particularly for dehydrohalogenation reactions and as a catalyst in condensation reactions like the Stobbe condensation.
Deprotonation Agent
Its sterically hindered nature makes it an effective, non-nucleophilic base for selectively removing protons from carbon acids, leading to carbanion formation in sophisticated synthetic pathways.
Polymerisation Initiator
It can serve as an initiator in certain anionic polymerisation processes, contributing to the controlled synthesis of polymers with specific molecular architectures.
| Molecular weight | 112.21 |
|---|---|
| Linear formula | (CH3)3COK |
| Assay | ≥97.0% (T) |
| Density | 0.82 g/mL at 25 °C |
| Concentration | 1.0 M in tert-butanol |
| Vapour pressure | 1 mmHg (220 °C) |
| Impurities tested | ≤2% K2(CO)3 and KOH |
| Melting point | 256-258 °C (dec.)(lit.) |


Hazard statements
- H228Flammable solid
- H252
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P235Keep cool
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3206 4.2/PG 2 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-35 |
| Safety statements (S) | 7/9-16-26-36/37/39-43-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium tert-butoxide used for?
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Potassium tert-butoxide is a strong, non-nucleophilic base primarily used in organic synthesis for dehydrohalogenation, deprotonation of carbon acids, and catalysing condensation reactions.
What is the CAS number and formula for Potassium tert-butoxide?
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The CAS number is 865-47-4, and its linear formula is (CH3)3COK.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Potassium tert-butoxide with an assay of ≥97.0% (T). We do not represent this product as USP, BP, or EP grade.
How should Potassium tert-butoxide be handled safely?
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Potassium tert-butoxide is flammable and corrosive. It reacts violently with water, necessitating handling under inert atmosphere with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. Refer to the safety data sheet for full details.
Is Potassium tert-butoxide a controlled substance?
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No, Potassium tert-butoxide is not listed as a controlled substance.
How is Potassium tert-butoxide packed and shipped?
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Products are packed in compliance with international shipping regulations. We export globally, ensuring safe transit. Please contact us for specific packaging details.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team via the website or provide your details, and we will respond promptly.
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