Tetramethylammonium fluoride
Tetramethylammonium fluoride (CAS 373-68-2), with the linear formula (CH₃)₄NF and a molecular weight of 93.14 g/mol, is a versatile reagent primarily utilised in chemical synthesis. It functions effectively as a fluoride source and is particularly noted for its utility in halogen exchange reactions and as a deprotecting agent. Available from Tech Serve Solutions, this compound supports various synthetic pathways in research and development.
- IUPAC
- TMAF
Halogen Exchange Reactions
Tetramethylammonium fluoride serves as a valuable reagent for facilitating halogen exchange processes in organic synthesis. Its fluoride anion can effectively displace other halogens, enabling the introduction of fluorine into organic molecules.
Deprotection Reagent
This compound is employed as a deprotecting agent in multi-step organic syntheses. It can selectively cleave certain protecting groups, regenerating functional groups for subsequent reactions.
Fluoride Source in Synthesis
As a readily available source of fluoride ions, tetramethylammonium fluoride is instrumental in various synthetic transformations where fluoride incorporation is required. It is useful in the preparation of fluorinated organic compounds.
| Molecular weight | 93.14 |
|---|---|
| Linear formula | (CH3)4NF |
| Assay | 97% |
| Application | Useful for halogen exchange. |
| Melting point | 170 °C (dec.)(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethylammonium fluoride used for?
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Tetramethylammonium fluoride (CAS 373-68-2) is primarily used in chemical synthesis as a reagent for halogen exchange reactions, as a deprotecting agent, and as a source of fluoride ions.
What are the CAS number and formula for Tetramethylammonium fluoride?
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The CAS number for Tetramethylammonium fluoride is 373-68-2, and its linear formula is (CH₃)₄NF.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethylammonium fluoride with an assay of 97%. TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the main safety hazards associated with Tetramethylammonium fluoride?
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Tetramethylammonium fluoride is classified with GHS07 (Warning) and carries hazard statements H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used.
How is Tetramethylammonium fluoride packed and exported?
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Tetramethylammonium fluoride is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of Tetramethylammonium fluoride, please contact our sales team through the website or by phone, providing your specific requirements.
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