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Tetramethylammonium chloride

CAS 75-57-0(CH3)4N(Cl)Chemical Synthesis

Tetramethylammonium chloride (CAS: 75-57-0), with the molecular formula (CH₃)₄N(Cl) and a molar mass of 109.60 g/mol, is a quaternary ammonium salt. It is a white crystalline solid readily soluble in methanol and water. This compound serves as a crucial reagent in chemical synthesis, particularly as a phase transfer catalyst, and is widely employed in research laboratories as an essential chemical.

IUPAC
TMA
Synonyms
TMA chlorideTetramethylammonium monochloride
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Tetramethylammonium chloride ((CH3)4N(Cl)) — chemical structure, CAS 75-57-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Ammonium SaltsChemical SynthesisEssential ChemicalsPhase Transfer CatalystsResearch EssentialsSaltsSynthetic Reagents More...
01 /Applications

Phase Transfer Catalysis

Tetramethylammonium chloride functions effectively as a phase transfer catalyst, facilitating reactions between reactants located in different immiscible phases. Its quaternary ammonium structure aids in transporting anions into organic phases, thereby accelerating reaction rates.

Chemical Synthesis

This compound is a valuable building block and reagent in various organic syntheses. It can be used to introduce the tetramethylammonium cation or serve as a precursor in the preparation of other organometallic compounds and specialty chemicals.

Electrolyte in Electrochemical Studies

Due to its ionic nature and solubility, tetramethylammonium chloride is frequently used as a supporting electrolyte in electrochemical research and applications, providing conductivity to solutions.

Research and Development

As a readily available and well-characterised chemical, it is a common reagent in academic and industrial research settings for exploring new chemical transformations and developing novel materials.

02 /Properties
Molecular weight109.60
Linear formula(CH3)4N(Cl)
Assay≥99.0% (AT)≥99.0%
Gradepurum
Solubilitymethanol: soluble0.1 g/mL, clear, colorless
Concentration5 M
Impurities tested≤2% water
Melting point>300 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H300Fatal if swallowed
  • H311Toxic in contact with skin
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P264Wash thoroughly after handling
  • P280Wear protective gloves, clothing and eye/face protection
  • P301IF SWALLOWED
  • P305IF IN EYES
  • P312Call a POISON CENTER if you feel unwell
Protective equipmentEyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)UN 2811 6.1 / PGII
Water hazard class (WGK, DE)1
Hazard codes (EU)T
Risk statements (R)21-25-36/37/38
Safety statements (S)26-28-36/37-45
Anion tracesbromide (Br-): ≤500 mg/kgsulfate (SO42-): ≤50 mg/kg

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
75-57-0
MDL number
MFCD00011628
Beilstein registry
3911201
05 /Additional specifications
Uv Absorptionλ: 260 nm Amax: 0.02λ: 280 nm Amax: 0.02
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Tetramethylammonium chloride primarily used for?

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Tetramethylammonium chloride (CAS: 75-57-0) is primarily used as a phase transfer catalyst and as a reagent in chemical synthesis and research applications.

What are the CAS number and chemical formula for Tetramethylammonium chloride?

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The CAS number for Tetramethylammonium chloride is 75-57-0, and its linear formula is (CH₃)₄N(Cl).

What grade and purity does Tech Serve Solutions supply for Tetramethylammonium chloride?

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Tech Serve Solutions supplies Tetramethylammonium chloride in purum grade with an assay of ≥99.0% (AT). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Tetramethylammonium chloride be handled safely?

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Tetramethylammonium chloride is classified as Danger, with hazards including acute toxicity (oral, dermal), skin irritation, serious eye irritation, and respiratory irritation (H300-H311-H315-H319-H335). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator, in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling procedures.

Is Tetramethylammonium chloride a controlled substance?

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Based on the provided data, Tetramethylammonium chloride (CAS: 75-57-0) is not indicated as a controlled or scheduled substance in major regulatory frameworks relevant to its classification.

How is Tetramethylammonium chloride shipped and exported?

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Tetramethylammonium chloride is classified under UN 2811, 6.1 / PGII, indicating it is shipped as a toxic solid. TSS is experienced in exporting chemicals globally, adhering to all relevant transportation and customs regulations.

How can I request a quote or sample for Tetramethylammonium chloride?

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To request a quote or sample for Tetramethylammonium chloride, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry, specifying the product name and CAS number.

Need Tetramethylammonium chloride in a specific grade or volume?