Tetramethylammonium fluoride tetrahydrate
Tetramethylammonium fluoride tetrahydrate (CAS 17787-40-5), with the molecular formula (CH₃)₄N(F) · 4H₂O and a molecular weight of 165.20 g/mol, is a versatile chemical reagent. It is primarily employed as a reactant in various organic synthesis reactions, including palladium-catalysed homocoupling of aryl halides and cross-coupling with alkenylsilanols. Additionally, it has applications in the fluorination of specific organic compounds and as an absorbent for hydrogen sulfide.
Homocoupling of Aryl Halides
Serves as a reactant in palladium-catalysed homocoupling reactions of aryl halides, facilitating the formation of carbon-carbon bonds.
Cross-Coupling Reactions
Utilised in cross-coupling reactions with alkenylsilanols, contributing to the synthesis of complex organic molecules.
Fluorination Agent
Acts as a reagent for the fluorination of specific compounds, such as dichloronitrobenzene, introducing fluorine atoms into organic structures.
Hydrogen Sulfide Absorption
Functions as a reversible absorbing agent for significant quantities of hydrogen sulfide in its liquid state, useful in gas treatment processes.
| Molecular weight | 165.20 |
|---|---|
| Linear formula | (CH3)4N(F) · 4H2O |
| Assay | 98% |
| Application | Reactant for:• Homocoupling of aryl halides via a palladium catalyzed mechanism1• Cross-coupling reactions with alkenylsilanols2• Fluorination of dichloronitrobenzene3Used as:• Reversible absorbing agent for large quantities of hydrogen sulfide in the liquid state4 |
| Melting point | 39-42 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 22-24/25-26-27 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethylammonium fluoride tetrahydrate used for?
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Tetramethylammonium fluoride tetrahydrate is used as a reactant in organic synthesis, including homocoupling and cross-coupling reactions, as a fluorinating agent, and as a reversible absorbent for hydrogen sulfide.
What is the CAS number and formula for Tetramethylammonium fluoride tetrahydrate?
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The CAS number is 17787-40-5, and the molecular formula is (CH₃)₄N(F) · 4H₂O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethylammonium fluoride tetrahydrate with an assay of 98%. This product is not intended for USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for handling this chemical?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Handle in a well-ventilated area and avoid dust formation.
Does TSS export Tetramethylammonium fluoride tetrahydrate?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Tetramethylammonium fluoride tetrahydrate.
How can I request a sample or quote for this product?
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To request a sample or a quote, please contact our sales team through the website or by calling our office. Please reference the product name and CAS number (17787-40-5).
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