Potassium methoxide
Potassium methoxide (CAS 865-33-8), with the molecular formula CH3OK and a molecular weight of 70.13 g/mol, is a potent organic base. It is a highly reactive compound, often supplied as a solution in methanol, and is primarily utilised as a strong base catalyst and reagent in various organic synthesis reactions, particularly in the pharmaceutical and fine chemical industries. Its reactivity necessitates careful handling and storage.
- IUPAC
- Potassium methylate
Strong Base Catalyst
Potassium methoxide serves as an effective strong base catalyst in numerous organic transformations, including transesterification, condensation reactions, and dehydrohalogenations, facilitating efficient chemical synthesis.
Reagent in Organic Synthesis
It is employed as a key reagent for deprotonation and nucleophilic substitution reactions within the scope of fine chemical and pharmaceutical intermediate manufacturing.
Deprotonation Agent
Its high basicity makes it suitable for the deprotonation of relatively weak carbon acids, enabling the formation of carbanions for subsequent synthetic steps.
| Molecular weight | 70.13 |
|---|---|
| Linear formula | CH3OK |
| Assay | 95% |
| Density | 0.95 g/mL at 20 °C |
| Refractive index | n20/D 1.37 |
| Concentration | ~25% in methanol (T) |
Hazard statements
- H251Self-heating; may catch fire
- H314Causes severe skin burns and eye damage
Precautionary statements
- P235Keep cool
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 11 °C / 51.8 °F |
| Transport (UN / ADR) | UN 3206 4.2/PG 2 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-34 |
| Safety statements (S) | 8-16-26-43-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium Methoxide used for?
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Potassium methoxide is primarily used as a strong base catalyst and reagent in organic synthesis, facilitating reactions such as transesterification, condensation, and dehydrohalogenation in the production of fine chemicals and pharmaceutical intermediates.
What is the CAS number and formula for Potassium Methoxide?
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The CAS number for Potassium Methoxide is 865-33-8, and its chemical formula is CH3OK.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Potassium Methoxide with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should Potassium Methoxide be handled safely?
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Potassium Methoxide is a highly reactive base that reacts violently with water and is corrosive. It is flammable and causes severe skin burns and eye damage. Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area, and keep away from water and ignition sources.
How is Potassium Methoxide shipped and exported?
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Potassium Methoxide is classified under UN 3206, Hazard Class 4.2, Packing Group II, indicating it is a spontaneously combustible solid, when not in solution. When supplied as a solution, such as approximately 25% in methanol, it is handled according to its specific transport classification. TSS is an experienced global exporter of chemicals.
How can I request a quote or sample for Potassium Methoxide?
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To request a quote or sample for Potassium Methoxide, please contact our sales department via the website or by phone, providing the product name, CAS number, and desired quantity.
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