Propylmagnesium chloride solution
Propylmagnesium chloride solution (CAS: 2234-82-4) is an organometallic compound with the linear formula CH3CH2CH2MgCl and a molecular weight of 102.85 g/mol. Supplied as approximately 2.0 M in diethyl ether, this reagent acts as a strong base and a nucleophile. It is primarily utilised in organic synthesis for the introduction of the n-propyl group into various molecules through Grignard reactions, facilitating carbon-carbon bond formation.
Grignard Reagent Synthesis
Propylmagnesium chloride is a classic Grignard reagent used to form carbon-carbon bonds. It reacts with electrophiles such as aldehydes, ketones, esters, and epoxides to introduce the n-propyl group into organic structures.
Organic Synthesis
This organometallic compound serves as a versatile building block in complex organic syntheses. Its strong nucleophilicity allows for efficient alkylation of various substrates, aiding in the construction of diverse molecular frameworks.
Organometallic Chemistry
As a key organometallic reagent, it is fundamental in exploring and developing new synthetic methodologies. Its reactivity profile makes it suitable for a range of transformations in academic and industrial research.
| Molecular weight | 102.85 |
|---|---|
| Linear formula | CH3CH2CH2MgCl |
| Density | 0.83 g/mL at 20 °C |
| Concentration | ~2.0 M in diethyl ether |
Hazard statements
- H225Highly flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H260In contact with water releases flammable gases
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P222Do not allow contact with air
- P223Do not allow contact with water
- P231Handle under inert gas
- P370In case of fire
- P422
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -40 °C / -40 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 1 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14/15-19-22-34-67 |
| Safety statements (S) | 16-26-36/37/39-43-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Propylmagnesium chloride solution used for?
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Propylmagnesium chloride solution is a Grignard reagent primarily used in organic synthesis for introducing the n-propyl group into molecules via carbon-carbon bond formation reactions.
What is the CAS number and formula for Propylmagnesium chloride solution?
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The CAS number is 2234-82-4 and the linear formula is CH3CH2CH2MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Propylmagnesium chloride solution as approximately 2.0 M in diethyl ether. This product is suitable for research and general synthesis purposes, and TSS does not represent it as USP, BP, or EP grade.
How should Propylmagnesium chloride solution be handled and stored?
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This substance is highly flammable and reacts violently with water, posing significant fire and explosion risks. It also causes severe skin burns and eye damage. Handle in a well-ventilated area, under an inert atmosphere, and away from ignition sources and water. Wear appropriate personal protective equipment, including gloves, eye protection, and respiratory protection.
How is Propylmagnesium chloride solution packed and shipped?
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Propylmagnesium chloride solution is packed and shipped according to strict safety regulations for hazardous materials, including flammable liquids and water-reactive substances, ensuring safe transport and export.
How can I request a sample or quote for Propylmagnesium chloride solution?
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Please contact our sales team via the website or direct inquiry to request a sample or obtain a quote for Propylmagnesium chloride solution.
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