Potassium 2-chloropyridine-3-trifluoroborate
Potassium 2-chloropyridine-3-trifluoroborate (CAS: 1201899-19-5) is an organotrifluoroborate compound with the molecular formula C5H3BClF3KN and a molecular weight of 219.44 g/mol. It serves as a stable and versatile surrogate for boronic acids in chemical synthesis. This compound is particularly valuable in organic chemistry for facilitating cross-coupling reactions and the introduction of substituted pyridine moieties into complex molecules.
- IUPAC
- Potassium (2-chloropyridin-3-yl)trifluoroborate,Potassium 2-chloro-3-pyridyltrifluoroborate
Organotrifluoroborates in Synthesis
Potassium 2-chloropyridine-3-trifluoroborate functions as a versatile building block in organic synthesis. Organotrifluoroborates are known for their stability and ease of handling compared to traditional boronic acids, making them suitable for various cross-coupling methodologies.
Suzuki-Miyaura Cross-Coupling Reactions
This trifluoroborate salt can participate in palladium-catalyzed Suzuki-Miyaura coupling reactions, enabling the formation of new carbon-carbon bonds. It is used to introduce the 2-chloropyridin-3-yl group into diverse organic frameworks.
Heteroaryl Chemistry
As a heteroaryl trifluoroborate, it is employed in the synthesis of complex molecules containing the pyridine ring system. This is relevant in the development of pharmaceuticals, agrochemicals, and materials science.
| Molecular weight | 219.44 |
|---|---|
| Empirical formula | C5H3BClF3KN |
| Assay | 97% |
| Application | Organotrifluoroborates as versatile and stable boronic acid surrogates. |
| Melting point | 220-225 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium 2-chloropyridine-3-trifluoroborate used for?
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Potassium 2-chloropyridine-3-trifluoroborate is primarily used as a reagent in organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura coupling, to introduce the 2-chloropyridin-3-yl moiety into target molecules.
What is the CAS number and formula for Potassium 2-chloropyridine-3-trifluoroborate?
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The CAS number is 1201899-19-5 and the empirical formula (Hill notation) is C5H3BClF3KN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Potassium 2-chloropyridine-3-trifluoroborate with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Potassium 2-chloropyridine-3-trifluoroborate be handled?
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This compound is classified as harmful if swallowed and causes skin and eye irritation. Handle with appropriate personal protective equipment, including gloves and eye protection. Ensure adequate ventilation and avoid dust formation. In case of contact, follow standard first aid procedures (e.g., rinse eyes thoroughly with water for several minutes).
Is Potassium 2-chloropyridine-3-trifluoroborate available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Potassium 2-chloropyridine-3-trifluoroborate.
How can I request a sample or quote for this chemical?
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To request a sample or a quotation for Potassium 2-chloropyridine-3-trifluoroborate, please contact our sales department through our website or by phone.
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