2-Methoxyphenylmagnesium bromide solution
2-Methoxyphenylmagnesium bromide solution (CAS: 16750-63-3), with the linear formula CH3OC6H4MgBr, is a valuable organometallic reagent. This Grignard reagent, supplied as a 1.0 M solution in diethyl ether, is primarily utilised in organic synthesis for introducing the 2-methoxyphenyl group into various molecular structures. Its reactivity makes it a key intermediate in the preparation of complex organic compounds across different chemical sectors.
Organic Synthesis
Used as a Grignard reagent to form new carbon-carbon bonds, facilitating the synthesis of complex organic molecules. It is instrumental in introducing the 2-methoxyphenyl moiety into target compounds.
Pharmaceutical Intermediate Production
Serves as a critical building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its controlled reactivity allows for precise molecular modifications.
Fine Chemical Manufacturing
Essential for the production of specialty and fine chemicals, where specific aryl group incorporation is required. It aids in the creation of novel compounds with tailored properties.
Materials Science Research
Investigated for its potential in the synthesis of advanced materials and polymers, contributing to the development of new substances with unique electronic or physical characteristics.
| Molecular weight | 211.34 |
|---|---|
| Linear formula | CH3OC6H4MgBr |
| Density | 0.791 g/mL at 25 °C |
| Concentration | 1.0 M in diethyl ether |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxyphenylmagnesium bromide solution primarily used for?
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2-Methoxyphenylmagnesium bromide solution is primarily used in organic synthesis for introducing the 2-methoxyphenyl group into various molecular structures via Grignard reactions.
What is the CAS number and formula for 2-Methoxyphenylmagnesium bromide solution?
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The CAS number is 16750-63-3, and the linear formula is CH3OC6H4MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 1.0 M solution in diethyl ether. We do not claim pharmacopoeia grades (USP, BP, EP) unless explicitly stated in the product specifications. For detailed analytical data, please consult the Certificate of Analysis.
How should 2-Methoxyphenylmagnesium bromide solution be handled safely?
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This solution is highly flammable (Flash Point: -17 °C) and can form explosive peroxides. It is also irritating to eyes and the respiratory system and is suspected of causing cancer. Handle with adequate ventilation in a fume hood, away from ignition sources, and wear appropriate personal protective equipment. Refer to the Safety Data Sheet (SDS) for comprehensive safety information.
How is 2-Methoxyphenylmagnesium bromide solution packed and shipped?
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The product is supplied as a solution in diethyl ether and is classified under UN 2056, Packing Group II. Shipping and handling adhere to regulations for flammable liquids. TSS is a global supplier and exporter experienced in handling hazardous materials.
How can I request a sample or quote for 2-Methoxyphenylmagnesium bromide solution?
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To request a sample or a detailed quote, please contact our sales team through the website or by phone. Provide your contact details and the required quantity.
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