2-Methoxyphenylzinc iodide solution
2-Methoxyphenylzinc iodide solution (CAS: 282727-20-2, Formula: CH3OC6H4ZnI, MW: 299.42) is an organozinc halide reagent offered by TSS. Supplied as a 0.5 M solution in THF, it is a versatile intermediate in organic synthesis. This reagent is commonly employed in cross-coupling reactions, enabling the formation of new carbon-carbon bonds. Its specific structure makes it valuable for introducing the 2-methoxyphenyl moiety into various organic frameworks, contributing to the synthesis of complex molecules in pharmaceutical and materials science research.
Cross-Coupling Reactions
2-Methoxyphenylzinc iodide is a key reagent in transition metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura or Negishi couplings. It facilitates the formation of C-C bonds by transferring the 2-methoxyphenyl group to an electrophilic partner.
Organic Synthesis Intermediate
This organozinc halide serves as a valuable building block in multi-step organic syntheses. It allows for the regioselective introduction of the 2-methoxyphenyl substituent into complex organic structures.
Synthesis of Pharmaceuticals
The 2-methoxyphenyl group is present in various biologically active molecules. This reagent can be utilized in the development and synthesis pathways of potential pharmaceutical compounds.
Materials Science
Organozinc reagents, including this compound, can find applications in the synthesis of functional materials and organic electronics where specific aryl substituents are required.
| Molecular weight | 299.42 |
|---|---|
| Linear formula | CH3OC6H4ZnI |
| Density | 0.996 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxyphenylzinc iodide solution used for?
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2-Methoxyphenylzinc iodide solution is primarily used as a reagent in organic synthesis, particularly in cross-coupling reactions to introduce the 2-methoxyphenyl group into organic molecules. It serves as a building block for complex molecule synthesis in areas like pharmaceuticals and materials science.
What is the CAS number and chemical formula for 2-Methoxyphenylzinc iodide solution?
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The CAS number is 282727-20-2, and the linear chemical formula is CH3OC6H4ZnI.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. TSS does not represent this product as USP, BP, or EP grade.
What are the key safety hazards associated with 2-Methoxyphenylzinc iodide solution?
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This solution is highly flammable (H225) and can cause serious eye irritation (H319) and respiratory irritation (H335). It is also suspected of causing cancer (H351) and may form explosive peroxides. Handle with extreme care in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment.
How is 2-Methoxyphenylzinc iodide solution shipped and exported?
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This product is classified under UN 2924, Hazard Class 8 (Corrosive) with a subsidiary Class 3 (Flammable) hazard, Packing Group II. Tech Serve Solutions is experienced in exporting hazardous materials, adhering to all international shipping regulations.
How can I request a sample or quote for 2-Methoxyphenylzinc iodide solution?
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To request a sample or a quotation, please use the contact form on our website or call our sales department directly. Please specify the quantity required and your shipping destination.
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