PNU112455A
PNU112455A, a hydrochloride salt of a complex organic molecule (CAS: 21886-12-4), presents as a white to beige powder. With the empirical formula C10H11N5O2S · HCl and a molecular weight of 301.75 g/mol, this compound is primarily utilised in biochemical research. It is especially relevant in the study of cell biology, cell signalling, and the intricate pathways involving cyclin-dependent kinases (CDKs) and serine/threonine kinases.
- IUPAC
- 4-[(6-amino-4-pyrimidinyl)amino]-benzenesulfonamide hydrochloride

Cell Biology Research
PNU112455A serves as a valuable tool in cell biology, aiding researchers in understanding fundamental cellular processes and signalling cascades.
Kinase Inhibitor Studies
This compound is employed in the investigation of kinase and phosphatase biology, particularly focusing on serine/threonine kinase pathways and their inhibition.
Neuroscience Research
Its relevance extends to neuroscience, where it can be used to probe cell signalling mechanisms relevant to neuronal function and dysfunction.
| Molecular weight | 301.75 |
|---|---|
| Empirical formula | C10H11N5O2S · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble5 mg/mL (clear solution) |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PNU112455A used for?
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PNU112455A is used in research settings for studies in cell biology, cell signalling, neuroscience, and particularly for investigating cyclin-dependent kinases (CDKs) and serine/threonine kinase pathways, including their inhibition.
What is the CAS number and chemical formula for PNU112455A?
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The CAS number for PNU112455A is 21886-12-4, and its chemical formula is C10H11N5O2S · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PNU112455A with a minimum purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade; it is supplied for research purposes.
How should PNU112455A be handled and stored?
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PNU112455A is classified as a Warning substance. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Store at 2-8°C. Avoid contact with skin, eyes, and clothing. If in eyes, rinse cautiously with water for several minutes and seek medical advice.
How is PNU112455A packed, shipped, and exported?
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PNU112455A is typically supplied as a powder in various packaging sizes suitable for laboratory use. Tech Serve Solutions is experienced in global export, adhering to all necessary shipping regulations for chemical products.
How can I request a sample or quote for PNU112455A?
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To request a sample or a quotation for PNU112455A, please contact our sales team directly through the website or by calling our office. Please specify the quantity required.
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