PP1

CAS 172889-26-8C16H19N5Cell Biology

PP1 (CAS: 172889-26-8), a pyrazolo[3,4-d]pyrimidine derivative with the molecular formula C16H19N5 and a molecular weight of 281.36 g/mol, is supplied as a white to off-white powder. This compound is recognised for its role in cell signalling research, particularly in relation to non-receptor tyrosine kinases. It is a valuable tool for investigations into kinase biology and its implications in cellular processes.

IUPAC: 4-Amino-5-(methylphenyl)-7-(t-butyl)pyrazolo-(3,4-d)pyrimidine

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PP1 (C16H19N5) — chemical structure, CAS 172889-26-8; Life Science, fine chemical supplied by Tech Serve Solutions

Cell BiologyKinase/Phosphatase BiologyPfizer Compounds

01 /Applications

Cellular Signalling Research

PP1 serves as a crucial reagent for studying intracellular signalling pathways, specifically those involving non-receptor tyrosine kinases like Src. Its use aids in understanding the molecular mechanisms governing cell growth, differentiation, and survival.

Kinase Inhibitor Studies

This compound is employed as an inhibitor in research focused on kinase and phosphatase biology. It helps elucidate the roles of these enzymes in various biological contexts, including potential therapeutic targets.

Neuroscience Investigations

Given its involvement in cell signalling, PP1 finds application in neuroscience research to explore signalling cascades within neuronal cells and their impact on neural function.

02 /Properties

Molecular weight	281.36
Empirical formula	C16H19N5
Assay	≥98% (HPLC)
Form	powder
Colour	white to off-white
Solubility	DMSO: >20 mg/mL
Storage temperature	room temp

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

172889-26-8

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is PP1 used for?

PP1 is primarily used in research for studying cell signalling pathways, kinase biology, and neuroscience, particularly as an inhibitor of non-receptor tyrosine kinases.

What are the CAS number and formula for PP1?

The CAS number for PP1 is 172889-26-8, and its molecular formula is C16H19N5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies PP1 with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should PP1 be handled and stored?

PP1 is classified as toxic if swallowed and requires careful handling. It should be stored at room temperature. Refer to the Safety Data Sheet for comprehensive handling and safety instructions. It is supplied with GHS06 hazard symbol and 'Danger' signal word, with hazard statement H301.

How is PP1 packaged and exported?

PP1 is supplied as a powder and is shipped at room temperature. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.