PNU-37883A
PNU-37883A (CAS: 57568-80-6) is a chemical compound with the molecular formula C21H36ClN3O and a molecular weight of 381.98 g/mol. This white powder is primarily utilized in scientific research, particularly within cell biology, cell signaling, and neuroscience. It functions as a modulator of ion channels, specifically targeting monovalent and voltage-gated ion channels. Its applications extend to the study of potassium channels, making it a valuable reagent for researchers in these fields.
- IUPAC
- N-(1-Adamantyl)-N′-cyclohexyl-4-morpholinecarboxamidine hydrochloride

Ion Channel Research
PNU-37883A serves as a vital tool for investigating the function and modulation of various ion channels, including monovalent and voltage-gated types. Researchers use it to understand channel kinetics and identify potential therapeutic targets.
Neuroscience Studies
This compound is employed in neuroscience research to explore cellular signaling pathways and neuronal function. Its interaction with potassium channels makes it relevant for studying nerve impulse transmission and neurological disorders.
Cell Biology Investigations
As a bioactive small molecule, PNU-37883A is instrumental in cell biology studies. It allows scientists to probe cellular processes influenced by ion channel activity and signaling pathways.
| Molecular weight | 381.98 |
|---|---|
| Empirical formula | C21H36ClN3O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: ~23 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... KCNJ8(3764) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PNU-37883A used for?
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PNU-37883A is used in scientific research for studying ion channels, cell signaling, neuroscience, and cell biology, particularly focusing on monovalent and voltage-gated ion channels such as potassium channels.
What is the CAS number and formula for PNU-37883A?
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The CAS number for PNU-37883A is 57568-80-6, and its molecular formula is C21H36ClN3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PNU-37883A with a purity of ≥98% (HPLC). TSS does not represent this product as USP, EP, BP, or any other pharmacopoeia grade.
What are the safety and handling requirements for PNU-37883A?
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PNU-37883A requires the use of Eyeshields, Gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It is classified with a WGK Germany rating of 3, indicating a high hazard to water.
How is PNU-37883A shipped and exported?
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PNU-37883A is typically stored at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter, adhering to all necessary regulations for international shipment.
How can I request a sample or quote for PNU-37883A?
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To request a sample or quote for PNU-37883A, please contact our sales department through the website or by phone.
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