Pivalic acid
Pivalic acid (CAS 75-98-9), also known as 2,2-dimethylpropionic acid, is a carboxylic acid with the linear formula (CH3)3CCO2H and a molecular weight of 102.13 g/mol. This white crystalline solid is a valuable building block in organic synthesis. Its sterically hindered tert-butyl group influences its reactivity, making it useful in the preparation of esters, amides, and polymers. Pivalic acid finds application in pharmaceuticals, agrochemicals, and as a ligand in catalysis.
- IUPAC
- 2,2-Dimethylpropionic acid,Trimethylacetic acid
- Synonyms
- 2,2-Dimethylpropionic acidTrimethylacetic acid
Organic Synthesis Intermediate
Pivalic acid serves as a key intermediate in the synthesis of various organic compounds. It is frequently used to introduce the pivaloyl group (tert-butylcarbonyl) into molecules, a moiety that can impart specific steric or electronic properties.
Pharmaceutical and Agrochemical Synthesis
The compound is employed in the multi-step synthesis of active pharmaceutical ingredients (APIs) and agrochemicals. Its structure allows for the creation of complex molecules with tailored biological activities.
Ligand and Catalyst Development
Pivalic acid derivatives can function as ligands in coordination chemistry and catalysis. These ligands can influence the selectivity and efficiency of catalytic transformations.
Polymer Additives and Monomers
It is used in the production of polymers and as an additive to modify polymer properties. Pivalic acid esters can act as plasticizers or monomers in specific polymerization processes.
| Molecular weight | 102.13 |
|---|---|
| Linear formula | (CH3)3CCO2H |
| Assay | 99% |
| Boiling point | 163-164 °C(lit.) |
| Density | 0.889 g/mL at 25 °C(lit.) |
| Vapour pressure | 9.75 mmHg (60 °C) |
| Vapour density | 3.6 (vs air) |
| Melting point | 32-35 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 64 °C / 147.2 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 21/22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pivalic acid used for?
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Pivalic acid is used as a building block in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, esters, amides, and polymers. It also finds use as a ligand in catalysis.
What is the CAS number and formula for Pivalic acid?
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The CAS number for Pivalic acid is 75-98-9 and its linear formula is (CH3)3CCO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pivalic acid with an assay of 99%. This product is suitable for research and general chemical synthesis; TSS does not represent it as USP, BP, or EP grade.
How should Pivalic acid be handled safely?
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Pivalic acid is corrosive and harmful if swallowed or inhaled. Handling requires appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. Always consult the Safety Data Sheet (SDS) before use.
Is Pivalic acid a controlled substance?
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The provided data does not indicate that Pivalic acid is a controlled substance.
How is Pivalic acid packed and exported by TSS?
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Pivalic acid is packed according to regulatory standards for hazardous materials. Tech Serve Solutions is experienced in exporting chemicals globally, ensuring compliance with international shipping regulations.
How can I request a quote or sample of Pivalic acid?
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To request a quote or a sample of Pivalic acid, please contact our sales department through the website or by phone, providing your specific requirements.
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