Phenylphosphine
Phenylphosphine (CAS 638-21-1), with the molecular formula C6H5PH2 and a molecular weight of 110.09 g/mol, is an organophosphorus compound. It serves as a key intermediate and building block in various chemical syntheses. Phenylphosphine is particularly valuable in the preparation of phosphine ligands for catalysis and in the development of novel organophosphorus materials.

Catalysis
Phenylphosphine is a precursor for synthesizing phosphine ligands, which are crucial in homogeneous catalysis for reactions like cross-coupling and hydrogenation.
Organic Synthesis
It acts as a versatile reagent in organic chemistry for introducing the phenylphosphino group into various organic molecules, enabling the construction of complex structures.
Materials Science
This compound can be utilised in the development of advanced phosphorus-containing polymers and materials with unique electronic or flame-retardant properties.
| Molecular weight | 110.09 |
|---|---|
| Linear formula | C6H5PH2 |
| Boiling point | 160 °C(lit.) |
| Density | 0.6912 g/mL at 25 °C1.001 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.578(lit.) |
| Vapour pressure | 760 mmHg (160 °C) |
| Vapour density | 3.79 (vs air) |
| Storage temperature | −20°C |




Hazard statements
- H225Highly flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H302Harmful if swallowed
- H304May be fatal if swallowed and enters airways
- H315Causes skin irritation
- H319Causes serious eye irritation
- H336May cause drowsiness or dizziness
- H361F
- H373May cause damage to organs through prolonged exposure
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P222Do not allow contact with air
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P422
| Flash point | -26 °C / -14.8 °F |
|---|---|
| Transport (UN / ADR) | UN 3384 3(6.1) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn,N |
| Risk statements (R) | 11-20/21/22-38-48/20-51/53-62-65 |
| Safety statements (S) | 16-36/37-61-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenylphosphine used for?
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Phenylphosphine is primarily used as an intermediate in chemical synthesis, particularly for preparing phosphine ligands used in catalysis and for developing organophosphorus materials.
What are the CAS number and chemical formula for Phenylphosphine?
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The CAS number for Phenylphosphine is 638-21-1, and its chemical formula is C6H5PH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenylphosphine in a technical/research grade. Purity details are available upon request, and TSS does not represent this product as USP, BP, or EP grade.
How should Phenylphosphine be handled safely?
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Phenylphosphine is a highly flammable liquid and vapour (H225), and can ignite spontaneously in air (H250). It is harmful if swallowed (H302), may be fatal if swallowed and enters airways (H304), causes skin irritation (H315), and serious eye irritation (H319). It may cause drowsiness or dizziness (H336), is suspected of damaging fertility or the unborn child (H361f), may cause damage to organs through prolonged or repeated exposure (H373), and is toxic to aquatic life with long lasting effects (H411). Always handle in a well-ventilated area, away from ignition sources, and use appropriate personal protective equipment.
Is Phenylphosphine a controlled substance?
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The provided data does not indicate that Phenylphosphine is a controlled substance.
How is Phenylphosphine packed and shipped?
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Phenylphosphine is packed and shipped according to international regulations for hazardous materials, including UN 3384 classification for transport. TSS exports globally.
How can I request a sample or quote for Phenylphosphine?
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To request a sample or a quote for Phenylphosphine, please contact our sales team through the website or by phone.
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