PhDave-Phos
PhDave-Phos (CAS: 240417-00-9, C26H24NP) is a phosphine ligand renowned for its efficacy in catalysing complex organic transformations. With a molecular weight of 381.45 g/mol, it is primarily employed in Buchwald-Hartwig cross-coupling reactions and carbon-carbon bond formation. This compound offers high catalytic activity, making it a valuable reagent for synthetic chemists in research and development settings requiring efficient and selective bond construction.
- IUPAC
- 2′-(Diphenylphosphino)-N,N′-dimethyl-(1,1′-biphenyl)-2-amine,2-Diphenylphosphino-2′-(N,N-dimethylamino)biphenyl,PhDavePhos
Buchwald-Hartwig Amination
PhDave-Phos is an effective ligand for palladium-catalysed Buchwald-Hartwig amination reactions, facilitating the formation of C-N bonds under mild conditions. It is widely used in the synthesis of complex amines relevant to pharmaceutical and agrochemical industries.
Carbon-Carbon Cross-Coupling
This phosphine ligand is instrumental in various palladium-catalysed carbon-carbon cross-coupling reactions. It enables the efficient construction of biaryl compounds and other complex carbon skeletons, crucial in advanced organic synthesis.
Catalysis in Organic Synthesis
As a versatile Buchwald ligand, PhDave-Phos plays a significant role in promoting challenging catalytic transformations. Its steric and electronic properties contribute to high yields and selectivity in various bond-forming processes.
| Molecular weight | 381.45 |
|---|---|
| Empirical formula | C26H24NP |
| Assay | 97% |
| Melting point | 122-126 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Ligand For | Buchwald-Hartwig Cross Coupling ReactionC-C Bond Formation |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PhDave-Phos used for?
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PhDave-Phos is primarily used as a ligand in palladium-catalysed cross-coupling reactions, particularly for Buchwald-Hartwig amination and carbon-carbon bond formation. It aids in the synthesis of complex organic molecules.
What is the CAS number and molecular formula for PhDave-Phos?
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The CAS number for PhDave-Phos is 240417-00-9, and its molecular formula is C26H24NP.
What grade and purity does Tech Serve Solutions supply for PhDave-Phos?
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Tech Serve Solutions supplies PhDave-Phos with an assay of 97%. TSS does not represent this product as USP, BP, or EP grade.
What are the safety precautions when handling PhDave-Phos?
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PhDave-Phos is a Warning-classified chemical (GHS07) that may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). When handling, use a dust mask type N95 (US), wear eyeshields and gloves, and avoid breathing dust. Ensure adequate ventilation and use in a well-ventilated area.
How is PhDave-Phos packed, shipped, and exported?
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PhDave-Phos is carefully packed to ensure stability and integrity during transit. As a global supplier, Tech Serve Solutions exports chemicals worldwide, adhering to all relevant shipping regulations for hazardous materials.
How can I request a sample or quote for PhDave-Phos?
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To request a sample or a quote for PhDave-Phos, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry.
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