Pentacosafluoro-1-iodododecane
Pentacosafluoro-1-iodododecane (CAS: 307-60-8), with the molecular formula CF3(CF2)11I and a molar mass of 745.99 g/mol, is a highly fluorinated organic compound. This perfluorinated alkyl iodide serves as a valuable building block in chemical synthesis. Its primary documented application involves its use in E-screen assays to study the estrogenic activities of polyfluorinated iodine alkanes, particularly in MCF-7 cell investigations.
- IUPAC
- 1-Iodoperfluorododecane,Perfluorododecyl iodide
- Synonyms
- 1-Iodoperfluorododecane, Perfluorododecyl iodide

Estrogenic Activity Research
Pentacosafluoro-1-iodododecane has been utilised in E-screen assays to evaluate the potential estrogenic activities of various polyfluorinated iodine alkanes. These studies often employ MCF-7 cells to investigate cellular responses.
Fluorinated Building Block
As a perfluorinated alkyl iodide, this compound functions as a key building block in organic synthesis. It enables the introduction of a long fluorinated chain into more complex molecular structures.
Chemical Synthesis Intermediate
The presence of the iodine atom makes Pentacosafluoro-1-iodododecane a reactive intermediate for various chemical transformations. It can participate in coupling reactions or other substitutions to create novel fluorinated materials.
| Molecular weight | 745.99 |
|---|---|
| Linear formula | CF3(CF2)11I |
| Assay | 97% |
| Boiling point | 108-110 °C/18 mmHg(lit.) |
| Application | Pentacosafluoro-1-iodododecane (1-Iodoperfluorododecane) has been used in E-screen assay to investigate the estrogenic activities of polyfluorinated iodine alkanes in MCF-7 cells1. |
| Melting point | 95-98 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pentacosafluoro-1-iodododecane used for?
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Pentacosafluoro-1-iodododecane is used as a building block in chemical synthesis and has been employed in E-screen assays to investigate the estrogenic activities of polyfluorinated iodine alkanes in MCF-7 cells.
What is the CAS number and formula for Pentacosafluoro-1-iodododecane?
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The CAS number is 307-60-8, and its linear formula is CF3(CF2)11I.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pentacosafluoro-1-iodododecane at a purity of 97% (Assay). This product is typically supplied for research and laboratory use and is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for Pentacosafluoro-1-iodododecane?
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Pentacosafluoro-1-iodododecane is classified as a Warning under GHS. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is Pentacosafluoro-1-iodododecane packed and exported?
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As a global supplier, Tech Serve Solutions exports chemicals worldwide, adhering to all relevant shipping and handling regulations for hazardous materials. Specific packaging details can be provided upon request.
How can I request a sample or quote for Pentacosafluoro-1-iodododecane?
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To request a sample or a quotation for Pentacosafluoro-1-iodododecane, please contact our sales team through the website or by phone. Our experts will be happy to assist you with your requirements.
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