2,2′-Difluorobiphenyl
2,2′-Difluorobiphenyl (CAS: 388-82-9) is a fluorinated aromatic compound with the linear formula C12H8F2 and a molecular weight of 190.19 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly in the development of advanced materials and complex organic molecules. Its specific structural features make it useful in creating compounds with tailored electronic and physical properties, driving innovation in research and development across various chemical sectors.
- Synonyms
- FC6H4C6H4F

Organic Synthesis Intermediate
2,2′-Difluorobiphenyl is utilised as a key intermediate in the synthesis of more complex organic molecules. Its reactive sites allow for further functionalisation, making it a versatile component in multi-step synthetic routes.
Materials Science Research
The compound's fluorinated biphenyl structure makes it of interest in materials science for the development of novel polymers and liquid crystals. Its properties can influence thermal stability and electronic characteristics of resulting materials.
Pharmaceutical Intermediate Development
As a fluorinated aryl building block, 2,2′-Difluorobiphenyl can be incorporated into the synthesis pathways for potential pharmaceutical candidates. Fluorine atoms are often introduced to modulate drug metabolism and binding affinity.
| Molecular weight | 190.19 |
|---|---|
| Linear formula | FC6H4C6H4F |
| Assay | 98% |
| Melting point | 117-121 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3152PSN1 9 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2′-Difluorobiphenyl used for?
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2,2′-Difluorobiphenyl is primarily used as an intermediate in organic synthesis, for materials science research, and in the development of potential pharmaceutical compounds. It functions as a fluorinated building block for creating complex organic structures.
What is the CAS number and formula for 2,2′-Difluorobiphenyl?
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The CAS number for 2,2′-Difluorobiphenyl is 388-82-9, and its linear formula is C12H8F2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2′-Difluorobiphenyl with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,2′-Difluorobiphenyl be handled safely?
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Based on its hazard statements (H315-H319-H335), 2,2′-Difluorobiphenyl can cause skin irritation, serious eye irritation, and may cause respiratory irritation. Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a dust mask type N95 (US). Ensure good ventilation.
Is 2,2′-Difluorobiphenyl a controlled substance?
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The provided data does not indicate that 2,2′-Difluorobiphenyl is a controlled substance.
How is 2,2′-Difluorobiphenyl packed and shipped?
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Tech Serve Solutions ensures chemicals are appropriately packed for international export, adhering to transport regulations such as UN 3152PSN1 9 / PGII.
How can I request a sample or quote for 2,2′-Difluorobiphenyl?
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To request a sample or a quotation for 2,2′-Difluorobiphenyl, please contact our sales department through the provided channels on the Tech Serve Solutions website.
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